Multimorbidity

Guthrie, Bruce; Skou, Søren T.; Mair, Frances S.; Miranda, J. Jaime; Nunes, Bruno P.; Boyd, Cynthia M.; Fortin, Martin; Smith, Susan M.; Pati, Sanghamitra; Mtenga, Sally

dc.contributor.author	Skou, Søren T.
dc.contributor.author	Mair, Frances S.
dc.contributor.author	Fortin, Martin
dc.contributor.author	Guthrie, Bruce
dc.contributor.author	Nunes, Bruno P.
dc.contributor.author	Miranda, J. Jaime
dc.contributor.author	Boyd, Cynthia M.
dc.contributor.author	Pati, Sanghamitra
dc.contributor.author	Mtenga, Sally
dc.contributor.author	Smith, Susan M.
dc.date.accessioned	2022-11-15T23:04:41Z
dc.date.available	2022-11-15T23:04:41Z
dc.date.issued	2022
dc.identifier.uri	https://hdl.handle.net/20.500.12866/12601
dc.description.abstract	Multimorbidity (two or more coexisting conditions in an individual) is a growing global challenge with substantial effects on individuals, carers and society. Multimorbidity occurs a decade earlier in socioeconomically deprived communities and is associated with premature death, poorer function and quality of life and increased health-care utilization. Mechanisms underlying the development of multimorbidity are complex, interrelated and multilevel, but are related to ageing and underlying biological mechanisms and broader determinants of health such as socioeconomic deprivation. Little is known about prevention of multimorbidity, but focusing on psychosocial and behavioural factors, particularly population level interventions and structural changes, is likely to be beneficial. Most clinical practice guidelines and health-care training and delivery focus on single diseases, leading to care that is sometimes inadequate and potentially harmful. Multimorbidity requires person-centred care, prioritizing what matters most to the individual and the individual’s carers, ensuring care that is effectively coordinated and minimally disruptive, and aligns with the patient’s values. Interventions are likely to be complex and multifaceted. Although an increasing number of studies have examined multimorbidity interventions, there is still limited evidence to support any approach. Greater investment in multimorbidity research and training along with reconfiguration of health care supporting the management of multimorbidity is urgently needed.	en_US
dc.language.iso	eng
dc.publisher	Springer
dc.relation.ispartofseries	Nature Reviews. Disease Primers
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Diseases	en_US
dc.subject	Risk factors	en_US
dc.subject	Therapeutics	en_US
dc.title	Multimorbidity	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1038/s41572-022-00376-4
dc.relation.issn	2056-676X