Successful Treatment of Primary Amoebic Meningoencephalitis Using a Novel Therapeutic Regimen Including Miltefosine and Voriconazole

Yhuri Carreazo, Nilton; Cabello Vílchez, Alfonso Martín; Martinez, Dalila Y.; Bravo-Cossio, Fanny; del Carmen Valdivia-Tapia, Maria

dc.contributor.author	Martinez, Dalila Y.
dc.contributor.author	Bravo-Cossio, Fanny
dc.contributor.author	del Carmen Valdivia-Tapia, Maria
dc.contributor.author	Yhuri Carreazo, Nilton
dc.contributor.author	Cabello Vílchez, Alfonso Martín
dc.date.accessioned	2022-11-15T23:04:41Z
dc.date.available	2022-11-15T23:04:41Z
dc.date.issued	2022
dc.identifier.uri	https://hdl.handle.net/20.500.12866/12604
dc.description.abstract	The genus Naegleria consists of free-living amoebae widely distributed worldwide in soil and freshwater habitats. Primary amoebic meningoencephalitis (PAM) is an uncommon and most likely fatal disease. The incubation period is approximately 7 days. The first symptoms are headache, nasal congestion, fever, vomiting, stiff neck within 3–4 days after the first symptoms, confusion, abnormal behavior, seizures, loss of balance and body control, coma, and death. We describe the case of a child who presented with PAM due to Naegleria sp., fully recovered from the infection without apparent sequels after treatment with a regimen that included miltefosine and voriconazole.	en_US
dc.language.iso	eng
dc.publisher	Springer
dc.relation.ispartofseries	Acta Parasitologica
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Naegleria	en_US
dc.subject	Central nervous system protozoal infections	en_US
dc.subject	Child	en_US
dc.subject	Miltefosine	en_US
dc.subject	Voriconazole	en_US
dc.title	Successful Treatment of Primary Amoebic Meningoencephalitis Using a Novel Therapeutic Regimen Including Miltefosine and Voriconazole	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1007/s11686-022-00591-9
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.07
dc.relation.issn	1896-1851