Universidad Peruana Cayetano Heredia

Human-mobility-related transmission of new parasite genetic clusters in Mazan basin in the Peruvian Amazon

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dc.contributor.author Manrique, Paulo
dc.contributor.author Nolasco, Oscar
dc.contributor.author Ramirez, Roberson
dc.contributor.author Miranda-Alban, J.
dc.contributor.author Carrasco-Escobar, Gabriel
dc.contributor.author Contreras-Mancilla Juan Jose
dc.contributor.author Rodriguez, Hugo
dc.contributor.author Speybroeck, Niko
dc.contributor.author Rosas-Aguirre, Angel
dc.contributor.author Llanos-Cuentas, Alejandro
dc.contributor.author Escalante, Ananias A.
dc.contributor.author Gamboa, Dionisia
dc.date.accessioned 2022-11-20T21:44:46Z
dc.date.available 2022-11-20T21:44:46Z
dc.date.issued 2019
dc.identifier.citation Manrique, P., Nolasco, O., Ramirez, R., Miranda-Alban, J., Carrasco-Escobar, G., Contreras-Mancilla J. J., Rodriguez, H., Speybroeck, N., Rosas-Aguirre, A., Llanos-Cuentas, A., Escalante, A. A. & Gamboa, D. (05 de septiembre, 2019). Human-mobility-related transmission of new parasite genetic clusters in Mazan basin in the Peruvian Amazon. [Presentación de póster]. XXII Jornadas Científicas 2019 “Dr. Eduardo Pretell Zárate”, Lima, Peru.
dc.identifier.uri https://hdl.handle.net/20.500.12866/12706
dc.description.abstract Plasmodium vivax is the main cause of malaria in the Peruvian Amazon and Mazan is considered one of its districts with high risk of malaria transmission. In this site, previous studies has described P. vivax transmission as heterogenic and has suggested that its prevalence is influenced by factors linked to human mobilization. However, the contribution of this factor have not been assessed yet. Population genetic tools provide information on the individual contribution of the factors that favor the transmission and evaluate the demographic patterns of dispersion of the parasite populations which are influenced by the human mobilization. In order to evaluate contribution of human mobilization to malariatransmission in Mazan, in this work we use a Bayesian framework to identify genetic sub-populations in each basin and to discriminate between endogenous and imported cases. Socio-demographic and clinical- epidemiological factors associated with the expansion of specific genetic sub- populations, the spatial distribution at a micro-geographical level of different genetic population parameters and the effects of the introduction of new genetic parasite populations on the clinical manifestations of the susceptible human population are also described.
dc.description.sponsorship Hacia la eliminación de la malaria en el Perú
dc.description.sponsorship UCSD - UPCH Global Infectious Diseases Training Programme: Endemic Infectious Diseases of the Peruvian Amazon
dc.description.sponsorship AMAZONIA-International Center of Excellence for Malaria Research
dc.description.sponsorship Joint project to strengthen research skills on molecular epidemiology and to uncover malaria transmission features relevant for its control in the Peruvian Amazon
dc.format application/pdf
dc.language.iso eng
dc.publisher Universidad Peruana Cayetano Heredia
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject Genética
dc.subject Parásitos
dc.title Human-mobility-related transmission of new parasite genetic clusters in Mazan basin in the Peruvian Amazon
dc.type info:eu-repo/semantics/conferenceObject
dc.description.conferenceDate 2019-09-05
dc.relation.conference XXII Jornadas Científicas 2019 “Dr. Eduardo Pretell Zárate”


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