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Hypoxia Predicts Lower Respiratory Tract Diseases in Adults Living at High Altitudes

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dc.contributor.author Leon-Abarca, Juan Alonso
dc.contributor.author Accinelli, Roberto Alfonso
dc.date.accessioned 2022-11-20T21:44:46Z
dc.date.available 2022-11-20T21:44:46Z
dc.date.issued 2019
dc.identifier.citation Leon-Abarca, J. A. & Accinelli, R. A. (05 de septiembre, 2019). Hypoxia Predicts Lower Respiratory Tract Diseases in Adults Living at High Altitudes. [Presentación de póster]. XXII Jornadas Científicas 2019 “Dr. Eduardo Pretell Zárate”, Lima, Peru.
dc.identifier.uri https://hdl.handle.net/20.500.12866/12708
dc.description.abstract Background: At sea level, tachypnea (respiratory rate> 24 / min) is a factor commonly associated with community-acquired pneumonia. However, in high altitudes, it must achieve higher rates, thus there is a need to look for other early predictors at these settings. Objective: This study aims to explore the presence of hypoxemia associated to the presence of diseases of the lower airways or not according to pulse oximetry readings. Methods: We used a database of 205071 18 to 65 year old altitude-resident outpatient adults in Cajamarca, Peru (2750 masl) as part of a private health program. Data was collected corresponding to demographic characteristics, vital functions (including peripheral oxygen saturation, SpO2) and individual diagnosis according to ICD-10 classification. The patients were divided into two groups according to the SpO2 level of 90% detected through a portable pulse oximeter. We used the Student’s T, the Mann-Whitney U test, logistic regression and proportions test for the analysis of means and differences in prevalence of diseases. The Stata 14.0 program was used for statistical analysis. Results: Diseases corresponding to the respiratory system were more common in patients with a SpO2 <90% (35.21% vs 32.11%, p <0.05). Of these patients, diseases of the lower tract were more common (2.72% vs 1.95%, p <0.05). These patients did not differ with age, heart rate, respiratory rate, blood pressure and temperature. Logistic regression shows that people with lower than 90% SpO2 are at a 40.7% higher risk of having lower respiratory tract infections (OR 1.407, 95%CI 1.26-1.56 p<0.0001). Conclusion: According to the results, high altitude adult residents who present to an outpatient clinic with an SpO2 <90% have a higher chance of presenting diseases of the lower respiratory tract, especially infections, supporting the use of pulse oximetry at high altitude outpatient settings as an early predictor of pneumonia.
dc.format application/pdf
dc.language.iso eng
dc.publisher Universidad Peruana Cayetano Heredia
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject Hypoxia
dc.subject Respiratory
dc.subject Adult
dc.subject High Altitude
dc.title Hypoxia Predicts Lower Respiratory Tract Diseases in Adults Living at High Altitudes
dc.type info:eu-repo/semantics/conferenceObject
dc.description.conferenceDate 2019-09-05
dc.relation.conference XXII Jornadas Científicas 2019 “Dr. Eduardo Pretell Zárate”

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