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Triazole resistance prevalence in Aspergillus fumigatus in Mexico and Peru

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dc.contributor.author Resendiz-Sharpe, Agustin
dc.contributor.author Bustamante, Beatriz
dc.contributor.author Merckx, R.
dc.contributor.author Jacobs, J.
dc.contributor.author Maertens,J.
dc.contributor.author Verweij,P.
dc.contributor.author Lagrou, K.
dc.date.accessioned 2022-11-20T21:44:48Z
dc.date.available 2022-11-20T21:44:48Z
dc.date.issued 2019
dc.identifier.citation Resendiz-Sharpe, A., Bustamante, B., Merckx, R., Jacobs, J., Maertens, J., Verweij, P. & Lagrou, K. (05 de septiembre, 2019). Triazole resistance prevalence in Aspergillus fumigatus in Mexico and Peru. [Presentación de póster]. XXII Jornadas Científicas 2019 “Dr. Eduardo Pretell Zárate”, Lima, Peru.
dc.identifier.uri https://hdl.handle.net/20.500.12866/12741
dc.description.abstract Introduction: Triazole-antifungal treatment, the recommended first-line therapy for aspergillosis, is threatened as triazole-resistance reports in Aspergillus fumigatus increase worldwide. Infection by resistant isolates not only occurs during prolonged triazole-treatments but also by inhalation of triazole-resistant spores from the environment. Modifications to the recommended initial triazole antifungal therapy have been proposed by an international expert consensus in centers with >10% environmental-resistance. However, triazole-resistance prevalence is not known in most countries as susceptibility testing is not routinely performed.Objective: To determine the prevalence of environmental triazole-resistant A. fumigatus in two Latin American countries, Mexico and Peru.Methodology: Environmental sampling. Triazole-resistance screening. Triazole-resistance confirmation.Results: A total of 304 soil samples were analyzed. Screening of environmental triazole-resistant A. fumigatus in Mexico and Peru.Conclusions: For the first time, triazole-resistant A. fumigatus was detected in soil samples in Mexico and Peru with a resistance prevalence of 6.9% and 9.8% respectively among A. fumigatus positive samples. Our findings emphasize the need to perform resistance screening or surveillance in clinical settings in these countries.
dc.format application/pdf
dc.language.iso eng
dc.publisher Universidad Peruana Cayetano Heredia
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject Triazole
dc.subject Aspergillus fumigatus
dc.subject Mexico
dc.subject Peru
dc.title Triazole resistance prevalence in Aspergillus fumigatus in Mexico and Peru
dc.type info:eu-repo/semantics/conferenceObject
dc.description.conferenceDate 2019-09-05
dc.relation.conference XXII Jornadas Científicas 2019 “Dr. Eduardo Pretell Zárate”

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