Universidad Peruana Cayetano Heredia
Agreement between the laboratory-based and non-laboratory-based WHO cardiovascular risk charts: a cross-sectional analysis of a national health survey in Peru
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| dc.contributor.author | Guzman Vilca, Wilmer Cristobal | |
| dc.contributor.author | Quispe-Villegas, Gustavo A. | |
| dc.contributor.author | Váscones Román, Fritz Fidel | |
| dc.contributor.author | Bernabé Ortiz, Antonio | |
| dc.contributor.author | Carrillo Larco, Rodrigo Martín | |
| dc.date.accessioned | 2022-12-14T14:25:33Z | |
| dc.date.available | 2022-12-14T14:25:33Z | |
| dc.date.issued | 2022 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/12871 | |
| dc.description.abstract | Objective To determine the agreement between the cardiovascular disease (CVD) risk predictions computed with the WHO non-laboratory-based model and laboratory-based model in a nationally representative sample of Peruvian adults. Design Cross-sectional analysis of a national health survey. Methods Absolute CVD risk was computed with the 2019 WHO laboratory-based and non-laboratory-based models. The risk predictions from both models were compared with Bland-Altman plots, Lin's concordance coefficient correlation (LCCC), and kappa statistics, stratified by sex, age, body mass index categories, smoking and diabetes status. Results 663 people aged 30-59 years were included in the analysis. Overall, there were no substantial differences between the mean CVD risk computed with the laboratory-based model 2.0% (95% CI 1.8% to 2.2%) and the non-laboratory-based model 2.0% (95% CI 1.8% to 2.1%). In the Bland-Altman plots, the limits of agreement were the widest among people with diabetes (-0.21; 4.37) compared with people without diabetes (-1.17; 0.95). The lowest agreement as per the LCCC was also seen in people with diabetes (0.74 (95% CI 0.63 to 0.82)), the same was observed with the kappa statistic (kappa=0.36). In general, agreement between the scores was appropriate in terms of clinical significance. Conclusions The absolute cardiovascular predicted risk was similar between the laboratory-based and non-laboratory-based 2019 WHO cardiovascular risk models. Pending validation from longitudinal studies, the non-laboratory-based model (instead of the laboratory-based) could be used when assessing CVD risk in Peruvian population. | en_US |
| dc.language.iso | eng | |
| dc.publisher | BMJ Group | |
| dc.relation.ispartofseries | BMJ Open | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
| dc.subject | laboratory-based | en_US |
| dc.subject | cardiovascular risk | en_US |
| dc.subject | national health survey | en_US |
| dc.subject | Peru | en_US |
| dc.title | Agreement between the laboratory-based and non-laboratory-based WHO cardiovascular risk charts: a cross-sectional analysis of a national health survey in Peru | en_US |
| dc.type | info:eu-repo/semantics/article | |
| dc.identifier.doi | https://doi.org/10.1136/bmjopen-2022-063289 | |
| dc.relation.issn | 2044-6055 |
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