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Dentinal tubules obliteration using a toothpaste with nano-hyDroxyapatite obtaineD from chicken eggshell

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dc.contributor.author Huamán-Mujica, Karina
dc.contributor.author Castañeda-Vía, José A.
dc.contributor.author Bermúdez García, Vanessa S.
dc.contributor.author Dominguez, John Alexis
dc.contributor.author Landauro, C. V.
dc.contributor.author Quispe-Marcatoma, J.
dc.contributor.author Tay Chu Jon, Lidia Yileng
dc.date.accessioned 2022-12-14T14:25:34Z
dc.date.available 2022-12-14T14:25:34Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/12891
dc.description.abstract Introduction: Dentin hypersensitivity is a common pathology, produced by exposed dental tubules. Objectives: The aim of this study was the evaluation of the effectiveness of experimental toothpaste based on nano-hydroxyapatite (nHAP) obtained from chicken eggshell in the obliteration of dentinal tubules (DTs). Material and methods: Toothpastes with different percentages of nHAP were formulated, including 3%, 7%, and 15% of nHAP, a commercial paste, and a toothpaste without nHAP. Assays were made using healthy premolar samples (n = 50). The pastes were applied and brushed for 7 days after a first erosive cycle, then a second erosive cycle was made at 15 days. Samples were analyzed using scanning electron microscopy and confocal Raman microscopy at three times: after the first erosive cycle (T0), after applications of the pastes (T7), and after the second erosive cycle (T15). Results: The quantitative analysis of the micrographs showed a significant difference between the experimental toothpastes with respect to the controls. Moreover, there was no statistically significant difference between the experimental toothpastes at time T7. By mineral concentration analysis, the 3%-nHAP toothpaste presented a significant difference against conventional toothpaste, when evaluating mineral concentration at 7 days. Conclusions: The experimental paste is effective in obliterating DTs at concentrations of 7 and 15%, in addition to being stable over time. en_US
dc.description.sponsorship Este trabajo fue parcialmente financiado por Concytec – Proyecto del Banco Mundial “Mejora y Expansión de los Servicios del Sistema Nacional de Ciencia, Tecnología e Innovación Tecnológica” 8682-PE, a través de su unidad ejecutora Fondecyt [Número de otorgamiento: 08-2018]. es_PE
dc.language.iso eng
dc.publisher Polish Dental Association
dc.relation.ispartofseries Journal of Stomatology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject microscopy en_US
dc.subject durapatite en_US
dc.subject eggshell en_US
dc.subject hypersensitivity en_US
dc.subject toothpastes en_US
dc.title Dentinal tubules obliteration using a toothpaste with nano-hyDroxyapatite obtaineD from chicken eggshell en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.5114/jos.2022.119082
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.14
dc.relation.issn 2299-551X


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