Universidad Peruana Cayetano Heredia

The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019

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dc.contributor.author Tran, K. B.
dc.contributor.author Lang, J. J.
dc.contributor.author Compton, K.
dc.contributor.author Xu, R. X.
dc.contributor.author Acheson, A. R.
dc.contributor.author Henrikson, H. J.
dc.contributor.author Kocarnik, J. M.
dc.contributor.author Penberthy, L.
dc.contributor.author Aali, A.
dc.contributor.author Abbas, Q.
dc.contributor.author Abbasi, B.
dc.contributor.author Abbasi-Kangevari, M.
dc.contributor.author Abbasi-Kangevari, Z.
dc.contributor.author Abbastabar, H.
dc.contributor.author Abdelmasseh, M.
dc.contributor.author Abd-Elsalam, S.
dc.contributor.author Abdelwahab, A. A.
dc.contributor.author Abdoli, G.
dc.contributor.author Abdulkadir, H. A.
dc.contributor.author Abedi, A.
dc.contributor.author Abegaz, K. H.
dc.contributor.author Abidi, H.
dc.contributor.author Aboagye, R. G.
dc.contributor.author Abolhassani, H.
dc.contributor.author Absalan, A.
dc.contributor.author Abtew, Y. D.
dc.contributor.author Ali, H. A.
dc.contributor.author Abu-Gharbieh, E.
dc.contributor.author Achappa, B.
dc.contributor.author Acuna, J. M.
dc.contributor.author Addison, D.
dc.contributor.author Addo, I. Y.
dc.contributor.author Adegboye, O. A.
dc.contributor.author Adesina, M. A.
dc.contributor.author Adnan, M.
dc.contributor.author Adnani, Q. E. S.
dc.contributor.author Advani, S. M.
dc.contributor.author Afrin, S.
dc.contributor.author Afzal, M. S.
dc.contributor.author Aggarwal, M.
dc.contributor.author Ahinkorah, B. O.
dc.contributor.author Ahmad, A. R.
dc.contributor.author Ahmad, R.
dc.contributor.author Ahmad, S.
dc.contributor.author Ahmadi, S.
dc.contributor.author Ahmed, H.
dc.contributor.author Ahmed, L. A.
dc.contributor.author Ahmed, M. B.
dc.contributor.author Rashid, T. A.
dc.contributor.author Aiman, W.
dc.contributor.author Ajami, M.
dc.contributor.author Akalu, G. T.
dc.contributor.author Akbarzadeh-Khiavi, M.
dc.contributor.author Aklilu, A.
dc.contributor.author Akonde, M.
dc.contributor.author Akunna, C. J.
dc.contributor.author Al Hamad, H.
dc.contributor.author Alahdab, F.
dc.contributor.author Alanezi, F. M.
dc.contributor.author Alanzi, T. M.
dc.contributor.author Alessy, S. A.
dc.contributor.author Algammal, A. M.
dc.contributor.author Al-Hanawi, M. K.
dc.contributor.author Alhassan, R. K.
dc.contributor.author Ali, B. A.
dc.contributor.author Ali, L.
dc.contributor.author Ali, S. S.
dc.contributor.author Alimohamadi, Y.
dc.contributor.author Alipour, V.
dc.contributor.author Aljunid, S. M.
dc.contributor.author Alkhayyat, M.
dc.contributor.author Al-Maweri, S. A. A.
dc.contributor.author Almustanyir, S.
dc.contributor.author Alonso, N.
dc.contributor.author Alqalyoobi, S.
dc.contributor.author Al-Raddadi, R. M.
dc.contributor.author Al-Rifai, R. H. H.
dc.contributor.author Al-Sabah, S. K.
dc.contributor.author Al-Tammemi, A. B.
dc.contributor.author Altawalah, H.
dc.contributor.author Alvis-Guzman, N.
dc.contributor.author Amare, F.
dc.contributor.author Ameyaw, E. K.
dc.contributor.author Dehkordi, J. J. A.
dc.contributor.author Amirzade-Iranaq, M. H.
dc.contributor.author Amu, H.
dc.contributor.author Amusa, G. A.
dc.contributor.author Ancuceanu, R.
dc.contributor.author Anderson, J. A.
dc.contributor.author Animut, Y. A.
dc.contributor.author Anoushiravani, A.
dc.contributor.author Anoushirvani, A. A.
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dc.contributor.author Antony, B.
dc.contributor.author Antwi, M. H.
dc.contributor.author Anwar, S. L.
dc.contributor.author Anwer, R.
dc.contributor.author Anyasodor, A. E.
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dc.contributor.author Al Artaman
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dc.contributor.author Asaad, M
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dc.contributor.author Asemi, Z
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dc.contributor.author Ashraf, T
dc.contributor.author Assadi, R
dc.contributor.author Athar, M
dc.contributor.author Athari, SS
dc.contributor.author Null, MMWA
dc.contributor.author Attia, S
dc.contributor.author Aujayeb, A
dc.contributor.author Ausloos, M
dc.contributor.author Avila-Burgos, L
dc.contributor.author Awedew, AF
dc.contributor.author Awoke, MA
dc.contributor.author Awoke, T
dc.contributor.author Quintanilla, BPA
dc.contributor.author Ayana, TM
dc.contributor.author Ayen, SS
dc.contributor.author Azadi, D
dc.contributor.author Null, SA
dc.contributor.author Azami-Aghdash, S
dc.contributor.author Azanaw, MM
dc.contributor.author Azangou-Khyavy, M
dc.contributor.author Jafari, AA
dc.contributor.author Azizi, H
dc.contributor.author Azzam, AYY
dc.contributor.author Babajani, A
dc.contributor.author Badar, M
dc.contributor.author Badiye, AD
dc.contributor.author Baghcheghi, N
dc.contributor.author Bagheri, N
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dc.contributor.author Bakhtiari, A
dc.contributor.author Bakshi, RK
dc.contributor.author Banach, M
dc.contributor.author Banerjee, I
dc.contributor.author Bardhan, M
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dc.contributor.author Barra, F
dc.contributor.author Barrow, A
dc.contributor.author Bashir, NZ
dc.contributor.author Bashiri, A
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dc.contributor.author Belay, AS
dc.contributor.author Belete, MA
dc.contributor.author Belgaumi, UI
dc.contributor.author Bell, AW
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dc.contributor.author Berhie, AY
dc.contributor.author Bermudez, ANC
dc.contributor.author Bernabe, E
dc.contributor.author Bhagavathula, AS
dc.contributor.author Bhala, N
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dc.contributor.author Bhardwaj, N
dc.contributor.author Bhardwaj, P
dc.contributor.author Bhattacharyya, K
dc.contributor.author Bhojaraja, VS
dc.contributor.author Bhuyan, SS
dc.contributor.author Bibi, S
dc.contributor.author Bilchut, AH
dc.contributor.author Bintoro, BS
dc.contributor.author Biondi, A
dc.contributor.author Birega, MGB
dc.contributor.author Birhan, HE
dc.contributor.author Bjorge, T
dc.contributor.author Blyuss, O
dc.contributor.author Bodicha, BBA
dc.contributor.author Bolla, SR
dc.contributor.author Boloor, A
dc.contributor.author Bosetti, C
dc.contributor.author Braithwaite, D
dc.contributor.author Brauer, M
dc.contributor.author Brenner, H
dc.contributor.author Briko, AN
dc.contributor.author Briko, NI
dc.contributor.author Buchanan, CM
dc.contributor.author Bulamu, NB
dc.contributor.author Bustamante-Teixeira, MT
dc.contributor.author Butt, MH
dc.contributor.author Butt, NS
dc.contributor.author Butt, ZA
dc.contributor.author dos Santos, FLC
dc.contributor.author Camera, LA
dc.contributor.author Cao, C
dc.contributor.author Cao, Y
dc.contributor.author Carreras, G
dc.contributor.author Carvalho, M
dc.contributor.author Cembranel, F
dc.contributor.author Cerin, E
dc.contributor.author Chakraborty, PA
dc.contributor.author Charalampous, P
dc.contributor.author Chattu, VK
dc.contributor.author Chimed-Ochir, O
dc.contributor.author Chirinos-Caceres, JL
dc.contributor.author Cho, D.Y.
dc.contributor.author Cho, WCS
dc.contributor.author Christopher, DJ
dc.contributor.author Chu, DT
dc.contributor.author Chukwu, IS
dc.contributor.author Cohen, AJ
dc.contributor.author Conde, J
dc.contributor.author Cortas, S
dc.contributor.author Costa, VM
dc.contributor.author Cruz-Martins, N
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dc.contributor.author Dahlawi, SMA
dc.contributor.author Dai, XC
dc.contributor.author Dandona, L
dc.contributor.author Dandona, R
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dc.contributor.author Danielewicz, A
dc.contributor.author Dao, ATM
dc.contributor.author Soltani, RDC
dc.contributor.author Darwesh, AM
dc.contributor.author Das, S
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dc.contributor.author Esmaeili, ED
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dc.contributor.author Debela, SA
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dc.contributor.author Molla, MD
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dc.contributor.author Deribe, KS
dc.contributor.author Desai, R
dc.contributor.author Desalegn, MD
dc.contributor.author Dessalegn, FN
dc.contributor.author Dessalegni, SAA
dc.contributor.author Dessie, G
dc.contributor.author Desta, AA
dc.contributor.author Dewan, SMR
dc.contributor.author Dharmaratne, SD
dc.contributor.author Dhimal, M
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dc.contributor.author Diao, N
dc.contributor.author Diaz, D
dc.contributor.author Digesa, LE
dc.contributor.author Dixit, SG
dc.contributor.author Doaei, S
dc.contributor.author Doan, LP
dc.contributor.author Doku, PN
dc.contributor.author Dongarwar, D
dc.contributor.author dos Santos, WM
dc.contributor.author Driscoll, TR
dc.contributor.author Dsouza, HL
dc.contributor.author Durojaiye, OC
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dc.contributor.author Eini, E
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dc.contributor.author Ekundayo, TC
dc.contributor.author Ekwueme, DU
dc.contributor.author El Tantawi, M
dc.contributor.author Elbahnasawy, MA
dc.contributor.author Elbarazi, I
dc.contributor.author Elghazaly, H
dc.contributor.author Elhadi, M
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dc.contributor.author Emamian, MH
dc.contributor.author Bain, LE
dc.contributor.author Enyew, DB
dc.contributor.author Erkhembayar, R
dc.contributor.author Eshetu, T
dc.contributor.author Eshrati, B
dc.contributor.author Eskandarieh, S
dc.contributor.author Espinosa-Montero, J
dc.contributor.author Etaee, F
dc.contributor.author Etemadimanesh, A
dc.contributor.author Eyayu, T
dc.contributor.author Ezeonwumelu, IJ
dc.contributor.author Ezzikouri, S
dc.contributor.author Fagbamigbe, AF
dc.contributor.author Fahimi, S
dc.contributor.author Fakhradiyev, IR
dc.contributor.author Faraon, EJA
dc.contributor.author Fares, J
dc.contributor.author Farmany, A
dc.contributor.author Farooque, U
dc.contributor.author Farrokhpour, H
dc.contributor.author Fasanmi, AO
dc.contributor.author Fatehizadeh, A
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dc.contributor.author Feleke, BE
dc.contributor.author Ferrari, AA
dc.contributor.author Ferrero, S
dc.contributor.author Desideri, LF
dc.contributor.author Filip, I
dc.contributor.author Fischer, F
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dc.contributor.author Foroutan, M
dc.contributor.author Fukumoto, T
dc.contributor.author Gaal, PA
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dc.contributor.author Gadanya, MA
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dc.contributor.author Gemeda, BNB
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dc.contributor.author Halwani, R
dc.contributor.author Hamadeh, RR
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dc.contributor.author Hasan, SMM
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dc.contributor.author Hashemi, SM
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dc.contributor.author Hlongwa, MM
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dc.contributor.author Hosseini, MS
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dc.contributor.author Hwang, BF
dc.contributor.author Ibitoye, SE
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dc.contributor.author Yousefi, Z
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dc.contributor.author Zastrozhin, MS
dc.contributor.author Zeineddine, MA
dc.contributor.author Zhang, DY
dc.contributor.author Zhang, JR
dc.contributor.author Zhang, YQ
dc.contributor.author Zhang, ZJ
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dc.contributor.author Murray, CJL
dc.date.accessioned 2022-12-14T14:25:34Z
dc.date.available 2022-12-14T14:25:34Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/12894
dc.description.abstract Background: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). Interpretation: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Lancet
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject cancer en_US
dc.subject risk factor en_US
dc.subject systematic analysis en_US
dc.subject Global Burden of Disease Study en_US
dc.title The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019 en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/S0140-6736(22)01438-6
dc.relation.issn 1474-547X


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