Universidad Peruana Cayetano Heredia
Association between multimorbidity with cognitive dysfunction in a Peruvian population.
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| dc.contributor.author | Carrasco-Zavala, J. | |
| dc.contributor.author | Díaz-Rg, J. A. | |
| dc.contributor.author | Bernabé Ortiz, Antonio | |
| dc.contributor.author | Lazo Porras, María de los Ángeles | |
| dc.coverage.spatial | Tumbes, Perú | |
| dc.date.accessioned | 2023-02-20T13:28:10Z | |
| dc.date.available | 2023-02-20T13:28:10Z | |
| dc.date.issued | 2023 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/13137 | |
| dc.description.abstract | BACKGROUND: Previous studies have shown that multimorbidity is a risk factor for cognitive dysfunction (CD).Type 2 diabetes mellitus (T2DM) and hypertension (HT) are very common risk factors.The association between multimorbidity due to both diseases and CD has been understudied in low and middle-income countries, in which the strength of the association might be stronger.AIM: To evaluate the association between multimorbidity due to T2DM and HT with CD among adults ≥50years in Tumbes.MATERIALS AND METHODS: A secondary analysis of a population-based cross-sectional study was conducted. The exposure variable was the presence of both T2DM and HT, split into categories: without HT or T2DM, only T2DM, only HT, and with T2DM and HT; whereas CD was the outcome variable, defined as a score≤26 in the Leganes Cognitive Test. Crude and adjusted generalized linear models were used to estimate the association of interest, and prevalence ratio (PR) and 95% confidence interval (95%CI) were reported.RESULTS: 688 participants were analyzed. The prevalence of CD was 39.1%. There was a 56.1% of participants without TDM2 nor HT, 8.3% with T2DM, 28.9% with HT and 6.7% with both diseases. A significant association was found between multimorbidity and CD (PR=1.43, 95%CI 1.04-1.97). Multimorbidity had a statistically significant association with CD in the group of participants with ≥7years of education (PR=2.56,95%CI 1.55-4.21), but no in the group with <7years.CONCLUSIONS: There is association between the morbidity of T2DM and HT, and CD among adults ≥50years of age in Tumbes. Education was an effect modifier of the association between HT and T2DM on the presence of CD. | en_US |
| dc.language.iso | eng | |
| dc.publisher | Elsevier | |
| dc.relation.ispartofseries | Journal of the Neurological Sciences | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
| dc.subject | Cognitive dysfunction | en_US |
| dc.subject | Hypertension | en_US |
| dc.subject | Diabetes mellitus | en_US |
| dc.subject | Diabetes mellitus type 2 | en_US |
| dc.subject | Multimorbidity | en_US |
| dc.subject.mesh | Cognitive Dysfunction | |
| dc.subject.mesh | Hypertension | |
| dc.subject.mesh | Diabetes Mellitus | |
| dc.subject.mesh | Diabetes Mellitus, Type 2 | |
| dc.subject.mesh | Multimorbidity | |
| dc.title | Association between multimorbidity with cognitive dysfunction in a Peruvian population. | en_US |
| dc.type | info:eu-repo/semantics/article | |
| dc.identifier.doi | https://doi.org/10.1016/j.jns.2023.120543 | |
| dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.02.25 | |
| dc.relation.issn | 1878-5883 |
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