DSpace Repository

Association between multimorbidity with cognitive dysfunction in a Peruvian population.

Show simple item record

dc.contributor.author Carrasco-Zavala, J.
dc.contributor.author Díaz-Rg, J. A.
dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Lazo Porras, María de los Ángeles
dc.coverage.spatial Tumbes, Perú
dc.date.accessioned 2023-02-20T13:28:10Z
dc.date.available 2023-02-20T13:28:10Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/13137
dc.description.abstract BACKGROUND: Previous studies have shown that multimorbidity is a risk factor for cognitive dysfunction (CD).Type 2 diabetes mellitus (T2DM) and hypertension (HT) are very common risk factors.The association between multimorbidity due to both diseases and CD has been understudied in low and middle-income countries, in which the strength of the association might be stronger.AIM: To evaluate the association between multimorbidity due to T2DM and HT with CD among adults ≥50years in Tumbes.MATERIALS AND METHODS: A secondary analysis of a population-based cross-sectional study was conducted. The exposure variable was the presence of both T2DM and HT, split into categories: without HT or T2DM, only T2DM, only HT, and with T2DM and HT; whereas CD was the outcome variable, defined as a score≤26 in the Leganes Cognitive Test. Crude and adjusted generalized linear models were used to estimate the association of interest, and prevalence ratio (PR) and 95% confidence interval (95%CI) were reported.RESULTS: 688 participants were analyzed. The prevalence of CD was 39.1%. There was a 56.1% of participants without TDM2 nor HT, 8.3% with T2DM, 28.9% with HT and 6.7% with both diseases. A significant association was found between multimorbidity and CD (PR=1.43, 95%CI 1.04-1.97). Multimorbidity had a statistically significant association with CD in the group of participants with ≥7years of education (PR=2.56,95%CI 1.55-4.21), but no in the group with <7years.CONCLUSIONS: There is association between the morbidity of T2DM and HT, and CD among adults ≥50years of age in Tumbes. Education was an effect modifier of the association between HT and T2DM on the presence of CD. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Journal of the Neurological Sciences
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Cognitive dysfunction en_US
dc.subject Hypertension en_US
dc.subject Diabetes mellitus en_US
dc.subject Diabetes mellitus type 2 en_US
dc.subject Multimorbidity en_US
dc.subject.mesh Cognitive Dysfunction
dc.subject.mesh Hypertension
dc.subject.mesh Diabetes Mellitus
dc.subject.mesh Diabetes Mellitus, Type 2
dc.subject.mesh Multimorbidity
dc.title Association between multimorbidity with cognitive dysfunction in a Peruvian population. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.jns.2023.120543
dc.relation.issn 1878-5883

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/restrictedAccess Except where otherwise noted, this item's license is described as info:eu-repo/semantics/restrictedAccess

Search DSpace


My Account