Browsing Artículos by Subject "Zebrafish/metabolism"

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Activation of zebrafish Src family kinases by the prion protein is an amyloid-beta-sensitive signal that prevents the endocytosis and degradation of

Sempou, Emily; Biasini, Emiliano; Pinzon-Olejua, Alejandro; Harris, David-A.; Málaga Trillo, George Edward (Springer, 2016)

BACKGROUND: Prions and amyloid-beta (Abeta) oligomers trigger neurodegeneration by hijacking a poorly understood cellular signal mediated by the prion protein (PrP) at the plasma membrane. In early zebrafish embryos, ...