ListarArtículos por tema "habitual adaptation"

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Genetic variants at the EGLN1 locus associated with high-altitude adaptation in Tibetans are absent or found at low frequency in highland Andeans

Heinrich, E.C.; Wu, L.; Lawrence, E.S.; Cole, A.M.; Anza-Ramirez, C.; Villafuerte, Francisco C.; Simonson, T.S. (Wiley, 2019)

EGLN1 encodes the hypoxia-inducible factor (HIF) pathway prolyl hydroxylase 2 (PHD2) that serves as an oxygen-sensitive regulator of HIF activity. The EGLN1 locus exhibits a signature of positive selection in Tibetan and ...