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Simultaneous RNA quantification of human and retroviral genomes reveals intact interferon signaling in HTLV-1-infected CD4+ T cell lines

Moens, B.; Pannecouque, C.; Lápez, G.; Talledo Albujar, Michael John; Gotuzzo Herencia, José Eduardo; Khouri, R.; Bittencourt, A.; Farré, L.; Galvão-Castro, B.; Vandamme, A.-M.; Van Weyenbergh, J. (BioMed Central, 2012)

Background: IFN- contributes extensively to host immune response upon viral infection through antiviral, pro-apoptotic, antiproliferative and immunomodulatory activities. Although extensively documented in various types ...