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The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci

D'Aeth, Joshua C.; van der Linden, Mark Pg; McGee, Lesley; de Lencastre, Herminia; Turner, Paul; Song, Jae-Hoon; Lo, Stephanie W.; Gladstone, Rebecca A.; Sá-Leão, Raquel; Ko, Kwan Soo; Hanage, William P.; Breiman, Robert F.; Beall, Bernard; Bentley, Stephen D.; Croucher, Nicholas J. (eLife Sciences Publications, 2021)

Multidrug-resistant Streptococcus pneumoniae emerge through the modification of core genome loci by interspecies homologous recombinations, and acquisition of gene cassettes. Both occurred in the otherwise contrasting ...