Universidad Peruana Cayetano Heredia

ListarEditados por otras instituciones por tema "Hypoxia"

ListarEditados por otras instituciones por tema "Hypoxia"

Ordenar por:Orden:Resultados:

  • Acid-base balance at high altitude in lowlanders and indigenous highlanders 
    Tymko, M.M.; Willie, C.K.; Howe, C.A.; Hoiland, R.L.; Stone, R.M.; Tymko, K.; Tymko, C.; MacLeod, D.; Anholm, J.D.; Gasho, C.; Villafuerte, Francisco C.; Vizcardo-Galindo, G.; Figueroa-Mujica, R.; Day, T.A.; Bird, J.D.; Foster, G.E.; Steinback, C.D.; Brugniaux, J.V.; Champigneulle, B.; Stauffer, E.; Doutreleau, S.; Verges, S.; Swenson, E.R.; Ainslie, P.N. (American Physiological Society, 2022)
    High-altitude exposure results in a hyperventilatory-induced respiratory alkalosis followed by renal compensation (bicarbonaturia) to return arterial blood pH (pHa) toward sea-level values. However, acid-base balance has ...
  • Aerobic capacity of Peruvian Quechua: a test of the developmental adaptation hypothesis 
    Kiyamu Tsuchiya, Melisa; Brutsaert, Tom D.; Elías, Gianpietro; León-Velarde, Fabiola; Rivera Chira, Maria Concepcion (Wiley, 2015)
    High altitude natives are reported to have outstanding work capacity in spite of the challenge of oxygen transport and delivery in hypoxia. To evaluate the developmental effect of lifelong exposure to hypoxia on aerobic ...
  • Association between serum concentrations of hypoxia inducible factor responsive proteins and excessive erythrocytosis in high altitude Peru 
    Painschab, M.S.; Malpartida, G.E.; Dávila-Roman, V.G.; Gilman, Robert Hugh; Kolb, T.M.; León-Velarde, Fabiola; Miranda, J. Jaime; Checkley, W. (Mary Ann Liebert, 2015)
    Long-term residence at high altitude is associated with the development of chronic mountain sickness (CMS), which is characterized by excessive erythrocytosis (EE). EE occurs under chronic hypoxia, and a strongly selected ...
  • Con: All dwellers at high altitude are persons of impaired physical and mental powers: The view from the andes 
    León-Velarde, Fabiola; Villafuerte, Francisco C. (Mary Ann Liebert, 2013)
    Despite the initial discomfort often experienced by visitors to high altitude (HA), humans have occupied the Andean altiplano for more than 10,000 years, and millions of people currently live on these plains, high in the ...
  • COVOX: Providing oxygen during the COVID-19 health emergency. 
    Rubio Grases, Joaquina; Rojas, Christiam; Sanchez, Midori; Gómez-Alzate, Daniela; Córdova, Mauricio; Montoya, Veronica; Castaneda, Benjamin; Chang, Javier; Pérez-Buitrago, Sandra (Elsevier, 2023)
    We introduce an autonomous oxygen concentrator that was designed in Peru to fight the oxygen shortage produced worldwide as a consequence of the COVID-19 pandemic. Oxygen concentrators represent a suitable and favorable ...
  • A cross-sectional study of differences in 6-min walk distance in healthy adults residing at high altitude versus sea level 
    Caffrey, Deirdre; Miranda, J. Jaime; Gilman, Robert Hugh; Davila-Roman, Victor G.; Cabrera, Lilia; Dowling, Russell; Stewart, Talia; Bernabé Ortiz, Antonio; Wise, Robert; León-Velarde, Fabiola; Checkley, William; CRONICAS Cohort (BioMed Central, 2014)
    Background: We sought to determine if adult residents living at high altitude have developed sufficient adaptation to a hypoxic environment to match the functional capacity of a similar population at sea level. To test ...
  • Developmental and genetic components explain enhanced pulmonary volumes of female peruvian quechua 
    Kiyamu Tsuchiya, Melisa; Bigham, A.; Parra, E.; León-Velarde, Fabiola; Rivera Chira, Maria Concepcion; Brutsaert, T.D. (Wiley, 2012)
    High altitude natives have enlarged vital capacities and residual volumes (RV). Because pulmonary volumes are an indication of functionally relevant traits, such as diffusion capacity, the understanding of the factors ...
  • Diabetes increases the risk of COVID-19 in an altitude dependent manner: An analysis of 1,280,806 Mexican patients 
    Leon-Abarca, Juan Alonso; Portmann Baracco, Arianna Sibila; Bryce-Alberti, M.; Ruiz-Sánchez, C.; Accinelli Tanaka, Roberto Alfonso; Soliz, J.; Gonzales Rengifo, Gustavo Francisco (Public Library of Science, 2021)
    Aims The objective of this study is to analyze how the impact of Diabetes Mellitus [DM] in patients with COVID-19 varies according to altitudinal gradient. Methods We obtained 1,280,806 records from adult patients with ...
  • Disturbed eating at high altitude: Influence of food preferences, acute mountain sickness and satiation hormones 
    Aeberli, Isabelle; Erb, Annina; Spliethoff, Kerstin; Meier, Daniela; Götze, Oliver; Frühauf, Heiko; Fox, Mark; Finlayson, Graham S.; Gassmann, Max; Berneis, Kaspar; Maggiorini, Marco; Langhans, Wolfgang; Lutz, Thomas A. (Springer, 2013)
    Purpose Hypoxia has been shown to reduce energy intake and lead to weight loss, but the underlying mechanisms are unclear. The aim was therefore to assess changes in eating after rapid ascent to 4,559 m and to investigate ...
  • Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans 
    Wojtal, Kacper A.; Cee, Alexandra; Lang, Silvia; Götze, Oliver; Frühauf, Heiko; Geier, Andreas; Pastor-Anglada, Marcal; Torres-Torronteras, Javier; Martí, Ramon; Fried, Michael; Lutz, Thomas A.; Maggiorini, Marco; Gassmann, Max; Rogler, Gerhard; Vavricka, Stephan R. (American Physiological Society, 2014)
    Solute carrier (SLC) transporters mediate the uptake of biologically active compounds in the intestine. Reduced oxygenation (hypoxia) is an important factor influencing intestinal homeostasis. The aim of this study was to ...
  • Effect of altitude on COVID-19 mortality rate and case incidence in Peru, the country with the highest cumulative mortality rate worldwide 
    Castillo Uribe, Valeria Alejandra; Cucho Vásquez, Betsabe Milagros; Contreras León, Zoë Lucía; Accinelli Tanaka, Roberto Alfonso; Huayanay Falconí, Leandro; Chu-Rivera, F.R. (Springer, 2023)
    Background: Peru had the highest COVID-19 cumulative mortality rate worldwide. A greater disadvantage in the population infected with COVID-19 living under chronic hypoxia would be expected. However, previous studies ...
  • Global REACH 2018: renal oxygen delivery is maintained during early acclimatization to 4,330 m 
    Steele, A.R.; Tymko, M.M.; Meah, V.L.; Simpson, L.L.; Gasho, C.; Dawkins, T.G.; Villafuerte, Francisco C.; Ainslie, P.N.; Stembridge, M.; Moore, J.P.; Steinback, C.D. (American Physiological Society, 2020)
    Early acclimatization to high altitude is characterized by various respiratory, hematological, and cardiovascular adaptations that serve to restore oxygen delivery to tissue. However, less is understood about renal function ...
  • High-Altitude Andean H194R HIF2A Allele Is a Hypomorphic Allele 
    Jorgensen, Kelsey; Song, Daisheng; Weinstein, Julien; Garcia, Obed A.; Pearson, Laurel N.; Inclán, María; Rivera Chira, Maria Concepcion; León-Velarde, Fabiola; Kiyamu Tsuchiya, Melisa; Brutsaert, Tom D.; Bigham, Abigail W.; Lee, Frank S. (Oxford University Press, 2023)
    For over 10,000 years, Andeans have resided at high altitude where the partial pressure of oxygen challenges human survival. Recent studies have provided evidence for positive selection acting in Andeans on the HIF2A (also ...
  • Highs and lows of sympathetic neurocardiovascular transduction: influence of altitude acclimatization and adaptation 
    Berthelsen, L.F.; Fraser, G.M.; Simpson, L.L.; Vanden Berg, E.R.; Busch, S.A.; Steele, A.R.; Meah, V.L.; Lawley, J.S.; Figueroa-Mujíca, R.J.; Vizcardo-Galindo, G.; Villafuerte, Francisco C.; Gasho, C.; Willie, C.K.; Tymko, M.M.; Ainslie, P.N.; Stembridge, M.; Moore, J.P.; Steinback, C.D. (American Physiological Society, 2020)
    High-altitude (>2,500 m) exposure results in increased muscle sympathetic nervous activity (MSNA) in acclimatizing lowlanders. However, little is known about how altitude affects MSNA in indigenous high-altitude populations. ...
  • The hypoxic placenta 
    Van Patot, M.C.T.; Ebensperger, G.; Gassmann, M.; Llanos, A.J. (Mary Ann Liebert, 2012)
    Hypoxia of the placenta is integral to complications of pregnancy, including preeclampsia, intrauterine growth restriction, and small-for-gestational age babies. Hypoxia in the placenta is associated with vascular remodeling, ...
  • Increased hypoxic proliferative response and gene expression in erythroid progenitor cells of Andean highlanders with Chronic Mountain Sickness. 
    Bermudez, Daniela; Azad, Priti; Figueroa-Mujica, Romulo; Vizcardo-Galindo, Gustavo; Corante, Noemi; Guerra-Giraldez, Cristina; Haddad, Gabriel G.; Villafuerte, Francisco C. (American Physiological Society, 2019)
    Excessive erythrocytosis (EE) is the main sign of Chronic Mountain Sickness (CMS), a maladaptive clinical syndrome prevalent in Andean and other high-altitude populations worldwide. The pathophysiological mechanism of EE ...
  • Is depression the link between suicide and high altitude? 
    Gamboa, J.L.; Caceda, R.; Arregui, A. (Mary Ann Liebert, 2011)
    Hypoxia is characteristic of living at high altitude. Animal and human studies have shown that chronic hypoxia is associated with changes in the brain. Neurological symptoms are common in high altitude populations. Headaches, ...
  • Is restless legs syndrome associated with chronic mountain sickness? 
    Vizcarra-Escobar, Darwin; Mendiola-Yamasato, Andrea; Risco-Rocca, Jorge; Marinos-Velarde, Alejandro; Juarez-Belaunde, Alan; Anculle-Arauco, Victor; Rivera Chira, Maria Concepcion (Elsevier, 2015)
    BACKGROUND: Restless legs syndrome (RLS) and chronic mountain sickness (CMS) share physiological traits. Our objective was to explore a possible association between RLS and CMS. METHODS: We carried a cross-sectional study ...
  • Ischemic changes in exercise ECG in a hypertensive subject acutely exposed to high altitude Possible role of a high-altitude induced imbalance in myocardial oxygen supply-demand 
    Caravita, Sergio; Faini, Andrea; Bilo, Grzegorz; Revera, Miriam; Giuliano, Andrea; Gregorini, Francesca; Rossi, Jessica; Villafuerte, Francisco C.; Salvi, Paolo; Agostoni, Piergiuseppe; Parati, Gianfranco (Elsevier, 2014)
    In the 1930–1940s Levy and coworkers administered low oxygen tension (thus simulating exposure to an altitude of about 5000 m) while monitoring ECG, in order to demonstrate coronary inadequacy resulting from imbalance ...
  • Left ventricular adaptation to high altitude: speckle tracking echocardiography in lowlanders, healthy highlanders and highlanders with chronic mountain sickness 
    Dedobbeleer, C.; Hadefi, A.; Pichon, A.; Villafuerte, Francisco C.; Naeije, R.; Unger, P. (Springer, 2015)
    Hypoxic exposure depresses myocardial contractility in vitro, but has been associated with indices of increased cardiac performance in intact animals and in humans, possibly related to sympathetic nervous system activation. ...

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