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Ophthalmic Manifestations of the Monkeypox Virus: A Systematic Review and Meta-Analysis

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dc.contributor.author Gandhi, Aravind P.
dc.contributor.author Gupta, Parul Chawla
dc.contributor.author Padhi, Bijaya K.
dc.contributor.author Sandeep, Mokanpally
dc.contributor.author Suvvari, Tarun Kumar
dc.contributor.author Shamim, Muhammad Aaqib
dc.contributor.author Satapathy, Prakasini
dc.contributor.author Sah, Ranjit
dc.contributor.author León Figueroa, Darwin Anthony
dc.contributor.author Rodriguez-Morales, Alfonso J.
dc.contributor.author Barboza, Joshuan J.
dc.contributor.author Dziedzic, Arkadiusz
dc.date.accessioned 2023-04-16T04:38:15Z
dc.date.available 2023-04-16T04:38:15Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/13394
dc.description.abstract Background: The accurate estimation of the prevalence of mpox-induced ophthalmic lesions will enable health departments to allocate resources more effectively during the ongoing mpox pandemic. The aim of this meta-analysis was to estimate the global prevalence of ophthalmic manifestations in mpox patients. Methods: A systematic search was carried out in seven databases—Pub Med, Scopus, Web of Science, EMBASE, ProQuest, EBSCOHost, and Cochrane—for studies published on or before 12 December 2022. The pooled prevalence of ophthalmic manifestations was estimated by the random effects model. Risk of bias assessment of the studies and sub-group analysis to explain heterogeneity were undertaken. Results: Overall, 12 studies were included, with 3239 confirmed mpox cases, among which 755 patients reported ophthalmic manifestations. The pooled prevalence of ophthalmic manifestations was 9% (95% confidence interval (CI), 3–24). Studies from Europe reported a very low prevalence of ocular manifestations of 0.98% (95% CI 0.14–2.31), compared to studies from Africa with a substantially higher prevalence of 27.22% (95% CI 13.69–43.26). Conclusions: A wide variation in the prevalence of ocular manifestations among mpox patients was observed globally. Healthcare workers involved in mpox-endemic African countries should be aware of ocular manifestations for early detection and management. © 2023 by the authors. en_US
dc.language.iso eng
dc.publisher Multidisciplinary Digital Publishing Institute
dc.relation.ispartofseries Pathogens
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject meta-analysis en_US
dc.subject mpox en_US
dc.subject ocular manifestations en_US
dc.subject outbreaks en_US
dc.title Ophthalmic Manifestations of the Monkeypox Virus: A Systematic Review and Meta-Analysis en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.3390/pathogens12030452
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 2076-0817


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