DSpace Repository

Long-term impact on cardiopulmonary function and quality of life among patients recovered from SARS-CoV-2 infection in a 6-month follow-up period in Lima, Peru: FUNCTION cohort study protocol.

Show simple item record

dc.contributor.author Cachay Figueroa, Rodrigo Antonio
dc.contributor.author Watanabe Tejada, Martín Takeshi
dc.contributor.author Cuno Quiñones, Katiuska Delia
dc.contributor.author Gil Zacarías, Marcela Dayana
dc.contributor.author Coombes Perez, Carolina Soledad
dc.contributor.author Ballena, Isabel
dc.contributor.author Mejía Cordero, Fernando Alonso
dc.contributor.author Medina Palomino, Félix Álvaro
dc.contributor.author Gayoso Cervantes, Oscar Danilo
dc.contributor.author Seas Ramos, Carlos Rafael
dc.contributor.author Otero Vegas, Larissa
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.coverage.spatial Lima, Perú
dc.date.accessioned 2023-05-19T14:08:33Z
dc.date.available 2023-05-19T14:08:33Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/13519
dc.description.abstract INTRODUCTION: The sequelae of COVID-19 have been described as a multisystemic condition, with a great impact on the cardiovascular and pulmonary systems with abnormalities in pulmonary function tests, such as lower diffusing capacity of the lung for carbon monoxide (DLco) levels and pathological patterns in spirometry; persistence of radiological lesions; cardiac involvement such as myocarditis and pericarditis; and an increase in mental disorders such as anxiety and depression. Several factors, such as infection severity during the acute phase as well as vaccination status, have shown some variable effects on these post-COVID-19 conditions, mainly at a clinical level such as symptoms persistence. Longitudinal assessments and reversibility of changes across the spectrum of disease severity are required to understand the long-term impact of COVID-19. METHODS AND ANALYSIS: A prospective cohort study aims to assess the impact of SARS-CoV-2 infection on cardiopulmonary function and quality of life after the acute phase of the disease over a 6-month follow-up period. Sample size was calculated to recruit 200 participants with confirmatory COVID-19 tests who will be subsequently classified according to infection severity. Four follow-up visits at baseline, month 1, month 3 and month 6 after discharge from the acute phase of the infection will be scheduled as well as procedures such as spirometry, DLco test, 6-minute walk test, chest CT scan, echocardiogram, ECG, N-terminal pro-B-type natriuretic peptide measurement and RAND-36 scale. Primary outcomes are defined as abnormal pulmonary function test considered as DLco <80%, abnormal cardiovascular function considered as left ventricular ejection fraction <50% and abnormal quality of life considered as a <40 score for each sphere in the RAND-36-Item Short Form Health Survey. en_US
dc.language.iso eng
dc.publisher BMJ Group
dc.relation.ispartofseries BMJ Open
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject cardiopulmonary en_US
dc.subject quality of life en_US
dc.subject patients en_US
dc.subject SARS-CoV-2 infection en_US
dc.subject Peru en_US
dc.subject.mesh Enfermedades Cardiovasculares
dc.subject.mesh Calidad de Vida
dc.subject.mesh Pacientes
dc.subject.mesh COVID-19
dc.subject.mesh Perú
dc.title Long-term impact on cardiopulmonary function and quality of life among patients recovered from SARS-CoV-2 infection in a 6-month follow-up period in Lima, Peru: FUNCTION cohort study protocol. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1136/bmjopen-2022-067365
dc.relation.issn 2044-6055


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/restrictedAccess Except where otherwise noted, this item's license is described as info:eu-repo/semantics/restrictedAccess

Search DSpace


Browse

My Account

Statistics