Universidad Peruana Cayetano Heredia

Monkeypox in Latin America and the Caribbean: assessment of the first 100 days of the 2022 outbreak

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dc.contributor.author Quispe, Antonio M.
dc.contributor.author Castagnetto Mizuaray, Jesús Martín
dc.date.accessioned 2023-05-19T14:08:34Z
dc.date.available 2023-05-19T14:08:34Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/13530
dc.description.abstract During the 2022 monkeypox (mpox) epidemic’s first 100 days, 99 non-endemic countries, including 25 Latin American and Caribbean (LAC) countries, reported >64,000 cases. We aim to assess the cases’ introduction, epidemiological profile, initial response, transmission dynamics, and main challenges ahead among LAC countries during the first 100 days of the mpox 2022 epidemic. We used mixed methods, including desktop research and open data analysis. The 2022 mpox epidemic has progressed consistently through LAC, with Brazil and Peru combining for over 80% of the confirmed LAC cases. Although Brazil reports the highest mpox case counts (n = 4472), Peru reports the highest incidence (41 confirmed cases per 1 million inhabitants). Initially, LAC missed the opportunity to focus on the high-risk population, including the people living with HIV (PLHIV) and gay, bisexual, and men who have sex with men (GBMSM). Moreover, the main challenges ahead include stigmatization, vaccine inequity, barriers to accessing diagnostics, and complete isolation. Furthermore, we estimated that Colombia, Brazil, the United States, and Peru are the world frontrunners in mpox duplication time (estimated between 6.4 and 8.8) and effective reproductive number (estimated between 2.7 and 3.8). In addition, Brazil reported its first case of inverse zoonosis in a dog and Peru its first autochthonous MPXV lineage, B.1.6. LAC has become the epicenter of the 2022 mpox epidemic, with Brazil and Peru emerging as the new mpox hot zones. Therefore, LAC countries must join efforts to control this epidemic and overcome the challenges of vaccine inequity and stigmatization. en_US
dc.language.iso eng
dc.publisher Taylor and Francis
dc.relation.ispartofseries Pathogens and Global Health
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Peru en_US
dc.subject Latin America en_US
dc.subject Brazil en_US
dc.subject Monkeypox en_US
dc.subject Caribbean region en_US
dc.subject basic reproduction number en_US
dc.subject epidemiological models en_US
dc.subject Poxviridae infections en_US
dc.subject.mesh Perú
dc.subject.mesh América Latina
dc.subject.mesh Brasil
dc.subject.mesh Viruela del Mono
dc.subject.mesh Región del Caribe
dc.subject.mesh Número Básico de Reproducción
dc.subject.mesh Modelos Epidemiológicos
dc.subject.mesh Infecciones por Poxviridae
dc.title Monkeypox in Latin America and the Caribbean: assessment of the first 100 days of the 2022 outbreak en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1080/20477724.2023.2201979
dc.relation.issn 2047-7732


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