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dc.contributor.author | Portmann Baracco, Arianna Sibila | |
dc.contributor.author | Alcorta Proaño, Rodrigo Gerónimo | |
dc.contributor.author | Nuñez Mochizaki, Claudia | |
dc.contributor.author | Webb Camminati, Camille María | |
dc.contributor.author | Trelles Yenque, Juan Gualberto | |
dc.contributor.author | Caparo Farfán, Carlos Alberto | |
dc.contributor.author | La Rosa de los Rios, Mauricio Francisco | |
dc.date.accessioned | 2023-06-12T16:25:54Z | |
dc.date.available | 2023-06-12T16:25:54Z | |
dc.date.issued | 2023 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/13602 | |
dc.description.abstract | OBJECTIVE: Evaluate the association between SARS-CoV-2 serologic status in immunologically naïve patients and risk of preeclampsia at time of delivery. STUDY DESIGN: We conducted a retrospective cohort study of pregnant patients admitted to our institution from August 1st to September 30th, 2020. We recorded maternal medical and obstetric characteristics, and SARS-CoV-2 serologic status. Our primary outcome was the incidence of preeclampsia. Antibody testing was performed and patients were classified into seropositive groups: IgG+, IgM+, or both IgG+ and IgM+. Bivariate and multivariable analyses were performed. RESULTS: We included 275 patients that were negative for SARS-CoV-2 antibodies, and 165 that were positive. Seropositivity was not associated with higher rates of preeclampsia (p=0.183), or with preeclampsia with severe features (p=0.916) even after adjusting for maternal age> 35, BMI≥ 30, nulliparity, and previous history of preeclampsia, and type of serologic status. Previous preeclampsia had the greatest association with development of preeclampsia (OR=13.40 95% CI [4.98-36.09]; p< 0.05), and with preeclampsia with severe features (OR=5.46 95% CI [1.65-18.02]; p< 0.05). CONCLUSIONS: We found that in an obstetric population there was no association between SARS-CoV-2 antibody status and the risk of preeclampsia. | en_US |
dc.language.iso | eng | |
dc.publisher | Georg Thieme Verlag KG | |
dc.relation.ispartofseries | American Journal of Perinatology | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | SARS-CoV-2 | en_US |
dc.subject | Antibody | en_US |
dc.subject | Delivery | en_US |
dc.subject | Risk | en_US |
dc.subject | Preeclampsia | en_US |
dc.subject.mesh | SARS-CoV-2 | |
dc.subject.mesh | Parto Obstétrico | |
dc.subject.mesh | Riesgo | |
dc.subject.mesh | Preeclampsia | |
dc.title | SARS-CoV-2 antibody status at time of delivery and the risk of preeclampsia. | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1055/a-2099-8758 | |
dc.relation.issn | 1098-8785 |
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