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Hemoglobin Levels in Peruvian Patients with Chronic Kidney Disease at Different Altitudes.

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dc.contributor.author Hurtado Aréstegui, Abdías Nicanor
dc.contributor.author Rosales Mendoza, Karina Janet
dc.contributor.author Venegas Justiniano, Joanna Yanissa
dc.contributor.author Gonzales-Polar, José
dc.contributor.author Barreto-Jara, Rina
dc.contributor.author Palacios-Guillén, Alaciel Melissa
dc.coverage.spatial Perú
dc.date.accessioned 2023-07-18T16:18:55Z
dc.date.available 2023-07-18T16:18:55Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/13916
dc.description.abstract Background: Decreased hemoglobin is a manifestation of chronic kidney disease (CKD), and people who reside at high altitude adapt to hypoxia by increasing their hemoglobin. The study's objective was to determine the influence of altitude and the associated factors on the hemoglobin levels of patients with CKD who were not on dialysis (ND). Methods: This exploratory and cross-sectional study was carried out in three Peruvian cities, located at different altitudes: (1) "sea level" (161 m), (2) "moderate altitude" (2,335 m), and "high altitude" (3,399 m). The study included female and male individuals between 20 and 90 years old, with CKD stage 3a, through stage 5. Results: Of the 256 volunteers evaluated, 92 lived at sea level, 82 at moderate altitude, and 82 at high altitude. The three groups were similar in age, number of volunteers in each CKD stage, systolic blood pressure, and diastolic blood pressure. Hemoglobin levels were statistically different according to gender (p = 0.024), CKD stage, and altitude (p < 0.001). High-altitude dwellers had higher hemoglobin by 2.5 g/dl (95% confidence interval: 1.8-3.1, p < 0.001) than those living at lower altitudes (adjusted for gender, age, nutritional status, and smoking habit). For all CKD stages, the high-altitude population had higher hemoglobin levels than population at moderate altitude and at sea level. Conclusion: Subjects living at high altitude with CKD stages 3 to 5 who are yet ND have higher hemoglobin levels than those who live at moderate altitude and at sea level. en_US
dc.language.iso eng
dc.publisher Mary Ann Liebert
dc.relation.ispartofseries High Altitude Medicine & Biology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Altitude en_US
dc.subject Chronic kidney disease en_US
dc.subject Hemoglobin en_US
dc.subject.mesh Altitud
dc.subject.mesh Insuficiencia Renal Crónica
dc.subject.mesh Hemoglobinas
dc.title Hemoglobin Levels in Peruvian Patients with Chronic Kidney Disease at Different Altitudes. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1089/ham.2023.0046
dc.relation.issn 1557-8682


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