Universidad Peruana Cayetano Heredia

Red blood cell distribution width to predict mortality in heart transplant recipients: a systematic review

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dc.contributor.author Acuña-Chávez, L.M.
dc.contributor.author Cruzalegui-Bazán, C.
dc.contributor.author Quispe-Vicuña, C.
dc.contributor.author Saldarriaga, C.
dc.contributor.author Contreras, J.
dc.contributor.author Chávez-Peche, J.A.
dc.contributor.author Alvarez-Vargas, M.
dc.contributor.author Segura Saldaña, Pedro Antonio
dc.date.accessioned 2023-07-18T16:18:56Z
dc.date.available 2023-07-18T16:18:56Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/13931
dc.description.abstract Red blood cell distribution width (RDW) has been shown to have prognostic value in a number of different clinical settings, such as cardiovascular disease, including heart failure. However, its prognostic value in heart transplant (HT) recipients remains unknown. The aim of this systematic review is to determine the prognostic value of pre-transplant RDW for mortality in HT recipients. There is a pre-published protocol of this review. The terms "Heart transplant", "Red cell distribution width" and their synonyms were used in the search strategy. PubMed/Medline, Embase, Scopus, Web of Science and LILACS were searched until May 17th, 2022, without date or language restrictions. Two authors independently carried out the selection, first by title and abstract, second by full-text revision. Discrepancies were discussed and resolved with three other authors. Quality of individual studies was assessed with Newcastle Ottawa Scale (NOS) for cohorts. After removing the duplicates, 3885 articles were identified. Four articles were included in the qualitative synthesis. Three studies were classified as "good quality": whereas one as "poor quality" according to NOS scale. All the included articles evaluated long-term mortality and one study also evaluated short-term mortality. In this one, a correlation between higher RDW values and short-term mortality was reported. Meanwhile, in all the studies, a high pre-HT RDW was a marker of long-term mortality following cardiac transplantation. Our review shows that an elevated on-admission RDW is associated with long-term mortality in heart transplantation recipients. en_US
dc.language.iso eng
dc.publisher Page Press Publications
dc.relation.ispartofseries Monaldi Archives for Chest Disease
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Heart transplantation en_US
dc.subject Prognosis en_US
dc.subject Red cell distribution width en_US
dc.subject.mesh Trasplante de Corazón
dc.subject.mesh Pronóstico
dc.subject.mesh Índices de Eritrocitos
dc.title Red blood cell distribution width to predict mortality in heart transplant recipients: a systematic review en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.4081/monaldi.2022.2402
dc.relation.issn 2532-5264


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