dc.contributor.author |
Cerna-López, J.A. |
|
dc.contributor.author |
Tejada-Llacsa, P.J. |
|
dc.contributor.author |
Valle-Farfán, F.A.D.J. |
|
dc.contributor.author |
Alarcón, Graciela S. |
|
dc.contributor.author |
Ugarte-Gil, M.F. |
|
dc.contributor.author |
Pimentel-Quiroz, V.R. |
|
dc.coverage.spatial |
Perú |
|
dc.date.accessioned |
2023-09-06T20:45:06Z |
|
dc.date.available |
2023-09-06T20:45:06Z |
|
dc.date.issued |
2023 |
|
dc.identifier.uri |
https://hdl.handle.net/20.500.12866/14046 |
|
dc.description.abstract |
Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population. |
en_US |
dc.description.abstract |
La dermatomiositis clínicamente amiopática (DMCA) se relaciona con anticuerpos dirigidos contra la proteína codificada por el gen asociado con la diferenciación del melanoma 5 (MDA5). Los pacientes con DMCA tienen un mayor riesgo de desarrollar enfermedad pulmonar intersticial rápidamente progresiva y neumomediastino espontáneo. Se presentan dos casos peruanos de DMCA asociada con enfermedad pulmonar intersticial rápidamente progresiva con neumomediastino espontáneo, uno de ellos positivo para anticuerpos anti-MDA5. Hasta nuestro conocimiento, este es el primer reporte de DMCA asociado con anti-MDA5 en la población peruana. |
es_PE |
dc.language.iso |
eng |
|
dc.language.iso |
spa |
|
dc.publisher |
Elsevier |
|
dc.relation.ispartofseries |
Revista Colombiana de Reumatologia |
|
dc.rights |
info:eu-repo/semantics/restrictedAccess |
|
dc.rights.uri |
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es |
|
dc.subject |
Anticuerpo anti-MDA5 |
es_PE |
dc.subject |
Dermatomiositis amiopática |
es_PE |
dc.subject |
Neumomediastino |
es_PE |
dc.subject.mesh |
Enfisema Mediastínico |
|
dc.title |
Dermatomiositis hipomiopática asociada con enfermedad pulmonar intersticial rápidamente progresiva complicada con neumomediastino: una revisión basada en casos |
es_PE |
dc.title.alternative |
Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review |
en_US |
dc.type |
info:eu-repo/semantics/review |
|
dc.identifier.doi |
https://doi.org/10.1016/j.rcreu.2021.06.001 |
|
dc.subject.ocde |
https://purl.org/pe-repo/ocde/ford#3.02.17 |
|
dc.relation.issn |
2027-9000 |
|