Prevalence of SARS-CoV-2 Variants and Disease Outcome of COVID-19 Patients in the Amazonas Region of Peru

Pajuelo-Reyes, Cecilia; Chenet, Stella M.; De La Cruz-Vargas, Jhony A.; Rojas, Luis M.; Campos, Christian J.; Tsukayama Cisneros, Pablo; Tapia-Limonchi, Rafael; Tejedo, Juan R.

dc.contributor.author	Campos, Christian J.
dc.contributor.author	Pajuelo-Reyes, Cecilia
dc.contributor.author	Rojas, Luis M.
dc.contributor.author	De La Cruz-Vargas, Jhony A.
dc.contributor.author	Tejedo, Juan R.
dc.contributor.author	Tapia-Limonchi, Rafael
dc.contributor.author	Tsukayama Cisneros, Pablo
dc.contributor.author	Chenet, Stella M.
dc.coverage.spatial	Amazonas, Perú
dc.date.accessioned	2023-09-06T20:45:10Z
dc.date.available	2023-09-06T20:45:10Z
dc.date.issued	2023
dc.identifier.uri	https://hdl.handle.net/20.500.12866/14091
dc.description.abstract	Peru was severely affected by COVID-19 with a fatality rate that reached up to 6%. In this study, the relationship between SARS-CoV-2 variants and COVID-19 disease outcome in Amazonas, a region of northeastern Peru, was evaluated. The variants were determined by genomic sequencing, and clinical-epidemiological data were collected from 590 patients between April 2021 and February 2022. There was no association between mortality and hospitalization with any of the variants, but we did find that Omicron is more likely to infect vaccinated and nonvaccinated people. A significant association was also found between unvaccinated patients and hospitalization. Interestingly, in the indigenous population, there were fewer hospitalizations than in the general population. In conclusion, SARS-CoV-2 variants were not associated with the disease outcome in the Amazonas region, and indigenous population were found to be less vulnerable to severe COVID-19 illness.	en_US
dc.language.iso	eng
dc.publisher	American Journal of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	SARS-CoV-2	en_US
dc.subject	COVID-19	en_US
dc.subject	Patients	en_US
dc.subject	Amazonas	en_US
dc.subject	Peru	en_US
dc.subject.mesh	SARS-CoV-2
dc.subject.mesh	COVID-19
dc.subject.mesh	Pacientes
dc.subject.mesh	Ecosistema Amazónico
dc.subject.mesh	Perú
dc.title	Prevalence of SARS-CoV-2 Variants and Disease Outcome of COVID-19 Patients in the Amazonas Region of Peru	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.22-0739
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645