Show simple item record Peeling, Rosanna W. Mabey, David Chen, Xiang-Sheng Garcia Funegra, Patricia Jannet 2023-09-06T20:45:10Z 2023-09-06T20:45:10Z 2023
dc.description.abstract Syphilis is a sexually and vertically transmitted bacterial infection caused by the bacterium Treponema pallidum. Its prevalence is high in low-income and middle-income countries, and its incidence has increased in high-income countries in the last few decades among men who have sex with men. Syphilis is a major cause of adverse pregnancy outcomes in low-income and middle-income countries. Clinical features include a primary chancre at the point of inoculation, followed weeks later by the rash of secondary syphilis, a latent period, and in some cases, involvement of the eyes, CNS, and cardiovascular systems. It is diagnosed serologically. A single intramuscular dose of long-acting benzathine penicillin is recommended for people who have had syphilis for less than 1 year and longer courses for people with late latent syphilis. Control strategies include screening and treatment of all pregnant women, and targeted interventions for groups at high risk. Vaccine development, research on antibiotic prophylaxis, and digital messaging as prevention strategies are ongoing. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Lancet
dc.rights info:eu-repo/semantics/restrictedAccess
dc.subject Syphilis en_US
dc.subject Seminar en_US
dc.subject Treponema pallidum en_US
dc.subject.mesh Sífilis
dc.subject.mesh Conferencias de salud
dc.subject.mesh Treponema pallidum
dc.title Syphilis en_US
dc.type info:eu-repo/semantics/article
dc.relation.issn 1474-547X

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