Universidad Peruana Cayetano Heredia

Awake surgery for glioma resection during pregnancy: a systematic review.

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dc.contributor.author Bocanegra Becerra, Jhon Ernesto.
dc.contributor.author Batista, Sávio
dc.contributor.author Costa Vieitas, Fernando
dc.contributor.author Takahashi, Rafael
dc.contributor.author Oliveira, Leonardo de Barros
dc.contributor.author Castillo Huerta, Nicole Mariela
dc.contributor.author Ludeña Esquivel, Alonso
dc.contributor.author Bertani, Raphael
dc.date.accessioned 2023-10-09T17:09:16Z
dc.date.available 2023-10-09T17:09:16Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/14206
dc.description.abstract Brain tumors are rarely present during pregnancy. However, they can severely impact the fetus and mother's well-being due to a complex interaction of disease and physiological factors. Moreover, awake surgery for gliomas has been scarcely reported during this life stage, and the nuances and techniques merit further investigation. Herein, we performed a systematic review of the literature about awake surgery for glioma resection during pregnancy. A total of six patients with a median age of 30.5 years (interquartile range: 40-27) were analyzed. Awake surgery was performed in the third trimester in 50% of patients (median time: 24.5 weeks) without reported intraoperative complications. Conscious sedation was achieved by remifentanil and propofol infusion in 67% of cases, and intraoperative fetal heart monitoring was utilized in 83% of cases. Most studies revealed good clinical maternal-fetal outcomes at follow-up; however, long-term safety effects remain undetermined and warrant further research. In conclusion, awake surgery for glioma resection under a multidisciplinary approach can be a reasonable treatment option for select patients during pregnancy. en_US
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartofseries Neurosurgical Review
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Awake surgery en_US
dc.subject Conscious sedation en_US
dc.subject Pregnancy en_US
dc.subject Glioma en_US
dc.title Awake surgery for glioma resection during pregnancy: a systematic review. en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1007/s10143-023-02135-9
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.25
dc.relation.issn 1437-2320


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