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Antibacterial Effect of Hypochlorous Acid on Bacteria Associated with the Formation of Periodontal Biofilms: An in vitro Pilot Study

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dc.contributor.author Millones-Gómez, P.A.
dc.contributor.author Novoa-Herrera, M.
dc.contributor.author Maurtua Torres, Dora Jesus
dc.contributor.author Bacilio Amaranto, Reyma Evelyn
dc.contributor.author Requena-Mendizábal, M.F.
dc.contributor.author Calla-Poma, R.
dc.contributor.author Rosales-Cifuentes, T.V.
dc.contributor.author Malpartida-Quispe, F.M.
dc.contributor.author Minchón-Medina, C.A.
dc.contributor.author Romero-Gamboa, J.C.
dc.contributor.author Pinella-Vega, M.
dc.contributor.author Ojeda-Gómez, R.C.
dc.coverage.spatial Universidad Peruana Cayetano Heredia, Lima, Perú
dc.date.accessioned 2023-12-05T17:47:57Z
dc.date.available 2023-12-05T17:47:57Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/14609
dc.description.abstract Objective: To evaluate the antibacterial effect of electrolytically generated hypochlorous acid on Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis. Material and Methods: In this in vitro experiment, the effect of hypochlorous acid (HOCl) on the strains S. gordonii, F. nucleatum, and P. gingivalis was evaluated using 4% sodium hypochlorite, 0.12% chlorhexidine, and distilled water as controls. The four groups were placed on each plate, and each group was replicated five times. The agar diffusion method by zones measurement was used. The data were processed with SPSS using the Kruskal-Wallis test and multiple comparison tests. Results: Hypochlorous acid showed an average inhibition halo of 9.28 mm on S. gordonii. As expected with distilled water, no zone of inhibition was noted for any of the bacteria, nor were zones of inhibition observed with HOCl for F. nucleatum and P. gingivalis. Conclusion: Hypochlorous acid showed antimicrobial properties against only S. gordonii and was less effective than 4% sodium hypochlorite and 0.12% chlorhexidine, although no significant differences were found between the latter. en_US
dc.language.iso eng
dc.publisher Universidade Estadual da Paraíba
dc.relation.ispartofseries Pesquisa Brasileira em Odontopediatria e Clinica Integrada
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Microbiology en_US
dc.subject Anti-Bacterial Agents en_US
dc.subject Hypochlorous Acid en_US
dc.subject Sodium Hypochlorite en_US
dc.subject.mesh Microbiología
dc.subject.mesh Antibacterianos
dc.subject.mesh Ácido Hipocloroso
dc.subject.mesh Hipoclorito de Sodio
dc.title Antibacterial Effect of Hypochlorous Acid on Bacteria Associated with the Formation of Periodontal Biofilms: An in vitro Pilot Study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1590/pboci.2023.074
dc.relation.issn 1983-4632


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