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Oral squamous cell carcinomas and oral potentially malignant disorders: A Latin American study

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dc.contributor.author Gilligan, Gerardo
dc.contributor.author Panico, René
dc.contributor.author Lazos, Jerónimo
dc.contributor.author Morelatto, Rosana
dc.contributor.author Belardinelli, Paola
dc.contributor.author Criscuolo, Ines
dc.contributor.author Bolesina, Nicolas
dc.contributor.author Molina Ávila, Ignacio
dc.contributor.author Pimentel Solá, Juan Martin
dc.contributor.author Rivarola, Emilce
dc.contributor.author Morgante, Maria Jimena
dc.contributor.author Ingrassia Tonelli, Maria Eugenia
dc.contributor.author Gimenez, Javier
dc.contributor.author Doratti, Pablo
dc.contributor.author Werner, Laura Cecilia
dc.contributor.author Prado-Ribeiro, Ana Carolina
dc.contributor.author Brandão, Thais Bianca
dc.contributor.author Vechiato-Filho, Aljomar Jose
dc.contributor.author Cuzzullin, Maria Claudia
dc.contributor.author Saldivia-Siracusa, Cristina
dc.contributor.author Lopes, Marcio Ajudarte
dc.contributor.author Agostini, Michelle
dc.contributor.author Romañach, Mario José
dc.contributor.author Abrahão, Aline Corrêa
dc.contributor.author Fonsêca, Thamyres Campos
dc.contributor.author Kaminagakura, Estela
dc.contributor.author Anbinder, Ana Lia
dc.contributor.author Santos Alves, Kamilla
dc.contributor.author de Almeida Lança, Maria Leticia
dc.contributor.author Sacsaquispe Contreras, Sonia Julia
dc.contributor.author Rodriguez Ibazetta, Karem Annelize
dc.contributor.author Gerber-Mora, Roberto
dc.contributor.author Aranda Romo, Saray
dc.contributor.author Tejeda Nava, Francisco Javier
dc.contributor.author Cordero-Torres, Karina
dc.contributor.author Moreno Silva, Ricardo
dc.contributor.author Gonzalez-Arriagada, Wilfredo
dc.contributor.author Toro, Raiza
dc.contributor.author Silveira, Felipe Martins
dc.contributor.author Gonzalez, Natalia
dc.contributor.author Vargas, Pablo Agustin
dc.contributor.author Santos-Silva, Alan Roger
dc.contributor.author Bologna-Molina, Ronell
dc.contributor.author Villarroel-Dorrego, Mariana
dc.contributor.author Martinez, Benjamin
dc.contributor.author Piemonte, Eduardo
dc.date.accessioned 2023-12-05T17:48:03Z
dc.date.available 2023-12-05T17:48:03Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/14660
dc.description.abstract Objective: To determine the frequency of oral squamous cell carcinoma (OSCC) associated or not with oral potentially malignant disorders (OPMD), and the epidemiological profile and traditional risk factors in Latin America. Methods: A retrospective observational study was conducted in 17 Latin American centres. There were included cases of OSCC, analysing age, gender, OSCC and their association with previous OPMD. Clinicopathological variables were retrieved. The condition of sequential-OSCC versus OSCC-de novo (OSCC-dn) was analysed concerning the aforementioned variables. Quantitative variables were analysed using Student's t-test, and qualitative variables with chi-square. Results: In total, 2705 OSCC were included with a mean age of 62.8 years old. 55.8% were men. 53.75% of the patients were smokers and 38% were common drinkers. The lateral tongue border was the most affected site (24.65%). There were regional variations in OPMD, being leukoplakia the most frequent. Of the overall 2705 OSCC cases, 81.4% corresponded to OSCC-dn, while s-OSCC were 18.6%. Regarding lip vermillion SCC, 35.7% corresponded to de novo lip SCC and 64.3% were associated with previous OPMD. Conclusions: In Latin America, OSCC-dn seems to be more frequent with regional variations of some clinical and histopathological features. Further prospective studies are needed to analyse this phenomenon. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries Oral Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Latin America en_US
dc.subject Leukoplakia en_US
dc.subject Oral cancer en_US
dc.subject Oral potentially malignant disorders en_US
dc.subject Oral squamous cell carcinoma en_US
dc.subject.mesh América Latina
dc.subject.mesh Leucoplasia
dc.subject.mesh Neoplasias de la Boca
dc.subject.mesh Trastornos Histiocíticos Malignos
dc.subject.mesh Carcinoma de Células Escamosas de Cabeza y Cuello
dc.title Oral squamous cell carcinomas and oral potentially malignant disorders: A Latin American study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1111/odi.14778
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.14
dc.relation.issn 1601-0825


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