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Clinical Characteristics of Neurocysticercosis in a Peruvian Population-Based Epilepsy Cohort: A Descriptive Cross-Sectional Study of Baseline Clinical Intake.

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dc.contributor.author Allen, Samantha E.
dc.contributor.author Moyano Vidal, Luz Maria
dc.contributor.author Wardle, Melissa T.
dc.contributor.author Guzman, Carolina
dc.contributor.author Sanchez-Boluarte, Sofia S.
dc.contributor.author Bonnet, Gabrielle
dc.contributor.author Bustos Palomino, Javier Arturo
dc.contributor.author O'Neal, Seth E.
dc.contributor.author García Lescano, Héctor Hugo
dc.coverage.spatial Tumbes, Perú
dc.coverage.spatial Piura, Perú
dc.date.accessioned 2023-12-07T22:33:23Z
dc.date.available 2023-12-07T22:33:23Z
dc.date.issued 2023
dc.identifier.uri https://hdl.handle.net/20.500.12866/14705
dc.description.abstract Background: This study presents the baseline characteristics of a community-level population of people with epilepsy (n = 1975) living in an area endemic for Taenia solium, the pathogen responsible for neurocysticercosis (NCC). Methods: Participants were sequentially enrolled in a clinical cohort from 2007 to 2020 in Tumbes, Peru. All participants provided demographic and clinical history and received clinical evaluations. Diagnostics, including neuroimaging, cysticercosis serologies, and EEG, were obtained where possible. The data presented are from the cross-sectional baseline assessment of cohort participants. Results: Approximately 38% of participants met the criteria for NCC. Those with NCC were more likely to have adult-onset epilepsy, as well as a longer duration of epilepsy, as compared to their counterparts without NCC. Overall, the data indicate a large treatment gap, with only approximately a quarter of the baseline population with prescriptions for anti-seizure medications. Conclusions: These data reveal a high proportion of NCC among people living with epilepsy in these communities, with limited health care resources. At baseline, 74% of the population were not receiving anti-seizure treatments. Further analyses of these data will clarify the natural history of the disease for this population. en_US
dc.language.iso eng
dc.publisher MDPI
dc.relation.ispartofseries Pathogens
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Epidemiology en_US
dc.subject Epilepsy en_US
dc.subject Neurocysticercosis en_US
dc.subject.mesh Epidemiología
dc.subject.mesh Epilepsia
dc.subject.mesh Neurocisticercosis
dc.title Clinical Characteristics of Neurocysticercosis in a Peruvian Population-Based Epilepsy Cohort: A Descriptive Cross-Sectional Study of Baseline Clinical Intake. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.3390/pathogens12111313
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 2076-0817


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