Tegumentary leishmaniasis and coinfections other than HIV

Polman, K.; Martinez, D. Y.; Adaui, Vanessa; Kaye, P. M.; Dujardin, J.; Llanos Cuentas, Elmer Alejandro; Boelaert, M.; Verdonck, K.

dc.contributor.author	Martinez, D. Y.
dc.contributor.author	Verdonck, K.
dc.contributor.author	Kaye, P. M.
dc.contributor.author	Adaui, Vanessa
dc.contributor.author	Polman, K.
dc.contributor.author	Llanos Cuentas, Elmer Alejandro
dc.contributor.author	Dujardin, J.
dc.contributor.author	Boelaert, M.
dc.date.accessioned	2018-03-22T23:38:49Z
dc.date.available	2018-03-22T23:38:49Z
dc.date.issued	2018
dc.identifier.uri	https://hdl.handle.net/20.500.12866/1473
dc.description.abstract	Infectious diseases are often studied one by one, but people can have more than one infection at the same time. This is likely to happen when different microorganisms are linked to specific geographical regions or living conditions. In this paper, we summarise the literature about infections occurring together with tegumentary leishmaniasis (TL), a disease of skin and mucosal tissues that is caused by Leishmania parasites. We found that in Latin America, patients with TL are often also infected with helminths or with Trypanosoma cruzi (the parasite that causes Chagas disease). Information from other parts of the world is scarce. Animal studies and observations in humans show that one infection can change the course of another infection, but how this happens is not well understood. When different infections affect the same patient at the same time, the diagnosis can be difficult, especially when different microorganisms are biologically similar, when they cause similar lesions, or when they are present in the same lesions. Treatment can also be difficult because some coinfections reduce the efficacy of the treatment against Leishmania and because some drug combinations can lead to cumulative adverse effects.	en_US
dc.language.iso	eng
dc.publisher	Public Library of Science
dc.relation.ispartofseries	PLoS Neglected Tropical Diseases
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Co-infections	en_US
dc.subject	Leishmania	en_US
dc.subject	Leishmaniasis	en_US
dc.subject	Trypanosoma cruzi	en_US
dc.subject	Helminth infections	en_US
dc.subject	Leprosy	en_US
dc.subject	Helminths	en_US
dc.subject	Lesions	en_US
dc.title	Tegumentary leishmaniasis and coinfections other than HIV	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1371/journal.pntd.0006125
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1935-2735