Browsing Artículos en revistas indizadas by Author "Rodriguez-Aliaga, Piere"

Now showing items 1-2 of 2

Knots can impair protein degradation by ATP-dependent proteases

San Martín, Álvaro; Rodriguez-Aliaga, Piere; Molina, José Alejandro; Martin, Andreas; Bustamante, Carlos; Baez, Mauricio (National Academy of Sciences, 2017)

ATP-dependent proteases translocate proteins through a narrow pore for their controlled destruction. However, how a protein substrate containing a knotted topology affects this process remains unknown. Here, we characterized ...
New insights into the regulatory mechanisms of ppGpp and DksA on Escherichia coli RNA polymerase-promoter complex

Doniselli, Nicola; Rodriguez-Aliaga, Piere; Amidani, Davide; Bardales, Jorge A.; Bustamante, Carlos; Guerra Giraldez, Daniel; Rivetti, Claudio (Oxford University Press, 2015)

The stringent response modulators, guanosine tetraphosphate (ppGpp) and protein DksA, bind RNA polymerase (RNAP) and regulate gene expression to adapt bacteria to different environmental conditions. Here, we use Atomic ...

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