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Listar Artículos en revistas indizadas por autor "Dujardin, Jean-Claude"

Mostrando ítems 1-9 de 9

Association of the Endobiont Double-Stranded RNA Virus LRV1 With Treatment Failure for Human Leishmaniasis Caused by Leishmania braziliensis in Peru and Bolivia

Adaui, Vanessa; Lye, Lon-Fye; Akopyants, Natalia S.; Zimic-Peralta, Mirko Juan; Llanos Cuentas, Elmer Alejandro; Garcia, Lineth; Maes, Ilse; De Doncker, Simonne; Dobson, Deborah E.; Arévalo Zelada, Jorge Luis; Dujardin, Jean-Claude; Beverley, Stephen M. (Oxford University Press, 2015)

Cutaneous and mucosal leishmaniasis, caused in South America by Leishmania braziliensis, is difficult to cure by chemotherapy (primarily pentavalent antimonials [Sb(V)]). Treatment failure does not correlate well with ...
A Case-Control Study on the Association Between Intestinal Helminth Infections and Treatment Failure in Patients With Cutaneous Leishmaniasis

Martínez, Dalila Y.; Llanos Cuentas, Elmer Alejandro; Dujardin, Jean-Claude; Polman, Katja; Adaui, Vanessa; Boelaert, Marleen; Verdonck, Kristien (Oxford University Press, 2020)

BACKGROUND: Endemic regions of cutaneous leishmaniasis (CL) and intestinal helminthiasis overlap. CL treatment with systemic pentavalent antimonial drugs (Sb(5+)) fails in 10%-30% of patients. The study objective was to ...
Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage

Jara, Marlene; Berg, Maya; Caljon, Guy; de Muylder, Geraldine; Cuypers, Bart; Castillo Pareja, Denis Helan; Maes, Ilse; Orozco, María Del Carmen; Vanaerschot, Manu; Dujardin, Jean-Claude; Arévalo Zelada, Jorge Luis (Public Library of Science, 2017)

It was recently hypothesized that Leishmania amastigotes could constitute a semi-quiescent stage characterized by low replication and reduced metabolic activity. This concept developed with Leishmania (Leishmania) mexicana ...
A novel marker, ARM58, confers antimony resistance to Leishmania spp

Nühs, Andrea; Schäfer, Carola; Zander, Dorothea; Trübe, Leona; Tejera Nevado, Paloma; Schmidt, Sonja; Arévalo Zelada, Jorge Luis; Adaui, Vanessa; Maes, Louis; Dujardin, Jean-Claude; Clos, Joachim (Elsevier, 2014)

Protozoa of the Leishmania genus cause a variety of disease forms that rank at the top of the list of neglected tropical diseases. Anti-leishmanial drugs based on pentavalent antimony have been the mainstay of therapy for ...
Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru

Dujardin, Jean-Claude; Bañuls, Anne-Laure; Llanos Cuentas, Elmer Alejandro; Alvarez, Eugenia; DeDoncker, Simonne; Jacquet, Diane; Le Ray, Dominique; Arévalo Zelada, Jorge Luis; Tibayrenc, Michel (Elsevier, 1995)

During an outbreak of tegumentary leishmaniasis that developed in the 1990s in the Eastern Andean valley of Huanuco, Peru, the coexistence of Andean (uta) and sylvatic leishmaniases was suspected for ecological and ...
Quantification of Leishmania (Viannia) Kinetoplast DNA in Ulcers of Cutaneous Leishmaniasis Reveals Inter-site and Inter-sampling Variability in Parasite Load

Suarez, Milagros; Valencia, B. M.; Jara, Marlene; Alba, Milena; Boggild, Andrea K.; Dujardin, Jean-Claude; Llanos Cuentas, Elmer Alejandro; Arévalo Zelada, Jorge Luis; Adaui, Vanessa (Public Library of Science, 2015)

BACKGROUND: Cutaneous leishmaniasis (CL) is a skin disease caused by the protozoan parasite Leishmania. Few studies have assessed the influence of the sample collection site within the ulcer and the sampling method on the ...
Real-time PCR assay for detection and quantification of Leishmania (Viannia) organisms in skin and mucosal lesions: Exploratory study of parasite load and clinical parameters

Jara, Marlene; Adaui, Vanessa; Valencia, Braulio M.; Martinez, Dalila; Alba, Milena; Castrillon, Carlos; Cruz, Maria; Cruz, Israel; Van der Auwera, Gert; Llanos Cuentas, Elmer Alejandro; Dujardin, Jean-Claude; Arévalo Zelada, Jorge Luis (American Society for Microbiology, 2013)

Earlier histopathology studies suggest that parasite loads may differ between cutaneous leishmaniasis (CL) and mucosal leishmaniasis (ML) lesions and between acute and chronic CL. Formal demonstration requires highly ...
Treatment failure in leishmaniasis: Drug-resistance or another (epi-) phenotype?

Vanaerschot, Manu; Dumetz, Franck; Roy, Syamal; Ponte-Sucre, Alicia; Arévalo Zelada, Jorge Luis; Dujardin, Jean-Claude (Taylor and Francis, 2014)

Two major leishmaniasis treatments have shown a significant decrease in effectiveness in the last few decades, mostly in the Indian subcontinent but also in other endemic areas. Drug resistance of Leishmania correlated ...
Unveiling drug-tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis.

Jara, Marlene; Arévalo Zelada, Jorge Luis; Llanos Cuentas, Elmer Alejandro; den Broeck, Frederik Van; Domagalska, Malgorzata Anna; Dujardin, Jean-Claude (Frontiers, 2023)

INTRODUCTION: Resistance against anti-Leishmania drugs (DR) has been studied for years, giving important insights into long-term adaptations of these parasites to drugs, through genetic modifications. However, microorganisms ...

Listar Artículos en revistas indizadas por autor "Dujardin, Jean-Claude"

Listar Artículos en revistas indizadas por autor "Dujardin, Jean-Claude"

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