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Kidney function in tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis users: a systematic review and meta-analysis of published literature and a multi-country meta-analysis of individual participant data

Schaefer, Robin; Amparo da Costa Leite, Pedro Henrique; Silva, Ronaldo; Abdool Karim, Quarraisha; Akolo, Christopher; Caceres Palacios, Carlos Fernando; Dourado, Ines; Green, Kimberly; Hettema, Anita; Hoornenborg, Elske; Jana, Smarajit; Kerschberger, Bernhard; Mahler, Hally; Matse, Sindy; McManus, Hamish; Molina, Jean-Michel; Reza-Paul, Sushena; Azwa, Iskandar; Shahmanesh, Maryam; Taylor, Doug; Vega-Ramirez, Hamid; Veloso, Valdiléa G.; Baggaley, Rachel; Dalal, Shona (Elsevier, 2022)

Background: Previous WHO guidance on tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis (PrEP) suggests measuring creatinine levels at PrEP initiation and regularly afterwards, which might represent barriers ...

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