Prutsky, Gabriela J.; Domecq, Juan Pablo; Erwin, Patricia J.; Briel, Matthias; Montori, Victor M.; Akl, Elie A.; Meerpohl, Jorge J.; Bassler, Dirk; Schandelmaier, Stefan; Walter, Stephen D.; Zhou, Qi; Coello, Pablo Alonso; Moja, Lorenzo; Walter, Martin; Thorlund, Kristian; Glasziou, Paul; Kunz, Regina; Ferreira-Gonzalez, Ignacio; Busse, Jason; Sun, Xin; Kristiansen, Annette; Kasenda, Benjamin; Qasim-Agha, Osama; Pagano, Genaro; Pardo-Hernandez, Hector; Urrutia, Gerard; Murad, Muhammad Hassan; Guyatt, Gordon
(BioMed Central, 2013)
Background: Randomized control trials (RCTs) stopped early for benefit (truncated RCTs) are increasingly common and, on average, overestimate the relative magnitude of benefit by approximately 30%. Investigators stop trials ...
