Universidad Peruana Cayetano Heredia

Listar Artículos en revistas indizadas por autor "Saavedra Pastor, Herbert"

Listar Artículos en revistas indizadas por autor "Saavedra Pastor, Herbert"

Ordenar por:Orden:Resultados:

  • Albendazole sulfoxide plasma levels and efficacy of antiparasitic treatment in patients with parenchymal neurocysticercosis 
    Arroyo Hurtado, Gianfranco; Bustos Palomino, Javier Arturo; Lescano Guevara, Andres Guillermo; Gonzales, Isidro; Saavedra Pastor, Herbert; Rodriguez, Silvia; Pretell, E. Javier; Bonato, Pierina S.; Lanchote, Vera L.; Takayanagui, Osvaldo M.; Horton, John; Gonzalez Zariquiey, Armando Emiliano; Gilman, Robert Hugh; García Lescano, Héctor Hugo (Oxford University Press, 2019)
    Background: The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable ...
  • Antibody banding patterns of the enzyme-linked immunoelectrotransfer blot and brain imaging findings in patients with Neurocysticercosis 
    Arroyo Hurtado, Gianfranco; Rodriguez, Silvia; Lescano Guevara, Andres Guillermo; Alroy, Karen A.; Bustos Palomino, Javier Arturo; Santivañez, Saul; Gonzales, Isidro; Saavedra Pastor, Herbert; Pretell, E. Javier; Gonzalez Zariquiey, Armando Emiliano; Gilman, Robert Hugh; Tsang, Victor C. W.; García Lescano, Héctor Hugo; Cysticercosis Working Group in Peru (Oxford University Press, 2018)
    Background: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections ...
  • Clinical topography relationship in patients with parenchymal neurocysticercosis and seizures 
    Duque, Kevin R.; Escalaya, Alejandro L.; Zapata, Willy; Burneo, Jorge G.; Bustos Palomino, Javier Arturo; Gonzales, Isidro; Saavedra Pastor, Herbert; Pretell, E. Javier; García Lescano, Héctor Hugo; Cysticercosis Working Group in Peru (Elsevier, 2018)
    OBJECTIVE: Discordances between imaging findings of parenchymal neurocysticercosis and seizure expression have been reported, and as such the possibility that neurocysticercosis and seizures may frequently coexist by chance ...
  • Combined antiparasitic treatment for neurocysticercosis - Authors' reply 
    García Lescano, Héctor Hugo; Gonzales, Isidro; Bustos Palomino, Javier Arturo; Saavedra Pastor, Herbert; Gavidia, Martin; Rodriguez, Lourdes; Najar Trujillo, Nestor Enrique; Umeres, Hugo; Pretell, E. Javier (Elsevier, 2015)
    We thank Aba Mahamat and colleagues for their comments on our Article1 and patient data illustrating a difficult case successfully treated with combined albendazole and praziquantel. We do not deem use of the combination ...
  • Cysticidal Efficacy of Combined Treatment With Praziquantel and Albendazole for Parenchymal Brain Cysticercosis 
    García Lescano, Héctor Hugo; Lescano Guevara, Andres Guillermo; Gonzales, Isidro; Bustos Palomino, Javier Arturo; Pretell, E. Javier; Horton, John; Saavedra Pastor, Herbert; Gonzalez Zariquiey, Armando Emiliano; Gilman, Robert Hugh (Oxford University Press, 2016)
    Background. The efficacy of current antiparasitic treatment for cerebral Taenia solium cysticercosis with either albendazole (ABZ) or praziquantel (PZQ) is suboptimal. A recent study demonstrated that combining these 2 ...
  • Detection of Taenia solium DNA in the urine of neurocysticercosis patients 
    Toribio, L.; Romano, M.; Scott, A.L.; Gonzales, I.; Saavedra Pastor, Herbert; García Lescano, Héctor Hugo; Shiff, C. (American Society of Tropical Medicine and Hygiene, 2019)
    Neurocysticercosis (NCC), caused by Taenia solium larvae that reside in the central nervous system, results in serious public health and medical issues in many regions of the world. Current diagnosis of NCC is complex ...
  • Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial 
    García Lescano, Héctor Hugo; Gonzales, Isidro; Lescano Guevara, Andres Guillermo; Bustos Palomino, Javier Arturo; Zimic-Peralta, Mirko Juan; Escalante, Diego; Saavedra Pastor, Herbert; Gavidia, Martin; Rodriguez, Lourdes; Najar Trujillo, Nestor Enrique; Umeres, Hugo; Pretell, E. Javier (Elsevier, 2014)
    BACKGROUND: Neurocysticercosis causes a substantial burden of seizure disorders worldwide. Treatment with either praziquantel or albendazole has suboptimum efficacy. We aimed to establish whether combination of these drugs ...
  • Enhanced steroid dosing reduces seizures during antiparasitic treatment for cysticercosis and early after 
    García Lescano, Héctor Hugo; Gonzales, Isidro; Lescano Guevara, Andres Guillermo; Bustos Palomino, Javier Arturo; Pretell, E.Javier; Saavedra Pastor, Herbert; Nash, Theodore E.; The Cysticercosis Working Group in Peru (Wiley, 2014)
    Objective: Neurocysticercosis (NCC) is a major cause of seizures and epilepsy in endemic countries. Antiparasitic treatment of brain cysts leads to seizures due to the host's inflammatory reaction, requiring concomitant ...
  • Frequency and determinant factors for calcification in neurocysticercosis 
    Bustos Palomino, Javier Arturo; Arroyo Hurtado, Gianfranco; Gilman, Robert Hugh; Soto Becerra, Percy; Gonzales, Isidro; Saavedra Pastor, Herbert; Pretell, E. Javier; Nash, Theodore E.; O'Neal, Seth E.; Del Brutto, Oscar H.; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo; Cysticercosis Working Group in Peru (Oxford University Press, 2021)
    BACKGROUND: Neurocysticercosis is a major cause of acquired epilepsy. Larval cysts in the human brain eventually resolve and either disappear or leave a calcification that is associated with seizures. In this study, we ...
  • Hippocampal Atrophy/Sclerosis Is Associated with Old, Calcified Parenchymal Brain Neurocysticercosis, But Not with More Recent, Viable Infections 
    Sanchez, Sofía S.; Bustos Palomino, Javier Arturo; Del Brutto, O.H.; Herrera, G.; dos Santos, A.C.; Pretell, E.J.; Gonzales, I.; Saavedra Pastor, Herbert; García Lescano, Héctor Hugo; Cysticercosis Working Grp Peru (American Society of Tropical Medicine and Hygiene, 2022)
    Magnetic resonance images from 197 patients with calcified neurocysticercosis (NCC), 38 with viable NCC and 197 NCC-free healthy rural villagers were evaluated to compare the frequency of hippocampal atrophy/sclerosis (HAS) ...
  • Improved diagnosis of viable parenchymal neurocysticercosis by combining antibody banding patterns on enzyme-linked immunoelectrotransfer blot (EITB) with antigen ELISA assay. 
    Arroyo Hurtado, Gianfranco; Bustos Palomino, Javier Arturo; Lescano Guevara, Andres Guillermo; Gonzales, Isidro; Saavedra Pastor, Herbert; Pretell, E. Javier; Castillo Berrios, Yesenia; Perez, Erika; Handali, Sukwan; Noh, John; Dorny, Pierre; Gilman, Robert Hugh; O'Neal, Seth E.; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo (American Society for Microbiology, 2022)
    The diagnosis of neurocysticercosis (NCC) depends on neuroimaging and serological confirmation. While antibody detection by enzyme-linked immunoelectrotransfer blot (EITB) fails to predict viable NCC, EITB banding patterns ...
  • Inflammation is a key risk factor for persistent seizures in neurocysticercosis 
    Herrick, Jesica A.; Maharathi, Biswajit; Kim, Jin Suh; Abundis, Gerardo G.; Garg, Anjali; Gonzales, Isidro; Saavedra Pastor, Herbert; Bustos Palomino, Javier Arturo; García Lescano, Héctor Hugo; Loeb, Jeffrey A.; Cysticercosis Working Group in Peru (Wiley, 2018)
    Objective: We conducted a retrospective, case-control study of neurocysticercosis patients to ascertain early markers that identify subjects likely to develop treatment-resistant seizures. Methods: Clinical histories and ...
  • A large silent cysticercus occupying most of the medulla oblongata 
    Meneses, J. P.; Salas, C.; Saavedra Pastor, Herbert; Esteban, D.; García Lescano, Héctor Hugo (Wiley, 2016)
    Neurocysticercosis (NCC) is the infectionof the central nervous system by cysts(larvae) of Taenia solium, a relevant pub-lic health issue in low-income countriesand nowadays found in most of theworld. NCC cysts most commonly ...
  • Low sensitivity and frequent cross-reactions in commercially available antibody detection ELISA assays for Taenia solium cysticercosis 
    García Lescano, Héctor Hugo; Castillo Berrios, Yesenia; Gonzales, Isidro; Bustos Palomino, Javier Arturo; Saavedra Pastor, Herbert; Jacob, Louis; Del Brutto, Oscar H.; Wilkins, Patricia P.; Gonzalez Zariquiey, Armando Emiliano; Gilman, Robert Hugh; Cysticercosis Working Group in Peru (Wiley, 2018)
    OBJECTIVE: To evaluate the diagnostic performance of two commercially available ELISA kits, Novalisa® and Ridascreen® , for the detection of antibodies to Taenia solium, compared to serological diagnosis of neurocysticercosis ...
  • Mortality in parenchymal and subarachnoid neurocysticercosis 
    Abanto, Jesús; Blanco, D.; Saavedra Pastor, Herbert; Gonzales, Isidro; Siu, Diego; Pretell, E. Javier; Bustos Palomino, Javier Arturo; García Lescano, Héctor Hugo; Cysticercosis Working Group in Peru (American Society of Tropical Medicine and Hygiene, 2021)
    Neurocysticercosis (NCC) is endemic in many parts of the world, carrying significant neurological morbidity that varies according to whether lesions are located inside the cerebral parenchyma or in extraparenchymal spaces. ...
  • Mycobacterium tuberculosis ribosomal protein S1 (RpsA) and variants with truncated C-terminal end show absence of interaction with pyrazinoic acid 
    Vallejos-Sánchez, K.; Lopez, J.M.; Antiparra, R.; Toscano, E.; Saavedra Pastor, Herbert; Kirwan, D.E.; Amzel, L.M.; Gilman, Robert Hugh; Maruenda, H.; Sheen Cortavarria, Patricia; Zimic-Peralta, Mirko Juan (Springer Nature, 2020)
    Pyrazinamide (PZA) is an antibiotic used in first- and second-line tuberculosis treatment regimens. Approximately 50% of multidrug-resistant tuberculosis and over 90% of extensively drug-resistant tuberculosis strains are ...
  • Neurocysticercosis. A frequent cause of seizures, epilepsy, and other neurological morbidity in most of the world 
    Bustos Palomino, Javier Arturo; Gonzales, Isidro; Saavedra Pastor, Herbert; Handali, Sukwan; García Lescano, Héctor Hugo; Cysticercosis Working Group in Peru (Elsevier, 2021)
    Neurocysticercosis is endemic in most of the world and in endemic areas it accounts for approximately 30% of cases of epilepsy. Appropriate diagnosis and management of neurocysticercosis requires understanding the diverse ...
  • Occasional resolution of multiple parenchymal brain calcifications in patients with neurocysticercosis 
    Meneses Quiroz, Luis Jean Pierre; Gonzales, Isidro; Pretell, Edwin Javier; Saavedra Pastor, Herbert; García Lescano, Héctor Hugo (Wolters Kluwer Health, 2015)
    Neurocysticercosis is the infection of the CNS by cysts (larvae) of Taenia solium, a worldwide tropical disease. Cysticercosis lesions frequently locate in the gray-white matter border of the cerebral hemispheres but also ...
  • Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis 
    García Lescano, Héctor Hugo; Lescano Guevara, Andres Guillermo; Lanchote, V.L.; Pretell, E.J.; Gonzales, I.; Bustos Palomino, Javier Arturo; Takayanagui, O.M.; Bonato, P.S.; Horton, J.; Saavedra Pastor, Herbert; Gonzalez Zariquiey, Armando Emiliano; Gilman, Robert Hugh (Wiley, 2011)
    Neurocysticercosis is the most common cause of acquired epilepsy in the world. Antiparasitic treatment of viable brain cysts is of clinical benefit, but current antiparasitic regimes provide incomplete parasiticidal efficacy. ...
  • Quality of life in patients with symptomatic epilepsy due to neurocysticercosis 
    Zapata, Willy R.; Yang, Susan Y.; Bustos Palomino, Javier Arturo; Gonzales, Isidro; Saavedra Pastor, Herbert; Guzman, Carolina; Pretell, E.Javier; García Lescano, Héctor Hugo; for The Cysticercosis Working Group In Peru (Elsevier, 2022)
    Background: Neurocysticercosis (NCC) is a common cause of late-onset epilepsy worldwide, but there is still minimal information regarding its impact on a patient's quality of life. This study evaluated quality of life in ...

Buscar en el Repositorio


Listar

Panel de Control