Universidad Peruana Cayetano Heredia

ListarArtículos en revistas indizadas por tema "Treponema pallidum"

ListarArtículos en revistas indizadas por tema "Treponema pallidum"

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  • Acquired oral syphilis: A multicenter study of 339 patients from South America 
    de Andrade, Bruno Augusto Benevenuto; de Arruda, José Alcides Almeida; Gilligan, Gerardo; Piemonte, Eduardo; Panico, René; Molina Ávila, Ignacio; Pimentel Sola, Juan Martin; Carmona Lorduy, Martha Cecilia; Pupo Marrugo, Stella; Sánchez Tatis, Angélica Sofia; Werner, Laura Cecilia; Abrahão, Aline Corrêa; Agostini, Michelle; Buoro, Luisa; Israel, Mônica Simões; Freire, Nathália de Almeida; Lima, Lucas Ambrósio; Abrantes, Thamiris de Castro; Cunha, John Lennon Silva; Pérez-de-Oliveira, Maria Eduarda; Roza, Ana Luiza Oliveira Corrêa; Vargas, Pablo Agustin; Lopes, Marcio Ajudarte; Santos-Silva, Alan Roger; de Almeida, Oslei Paes; Pontes, Flávia Sirotheau Corrêa; Pontes, Hélder Antônio Rebelo; Rondanelli, Benjamin Martínez; Villarroel-Dorrego, Mariana; Bologna-Molina, Ronell; Derderian, Nathalie; Sánchez-Romero, Celeste; Abreu, Lucas Guimarães; Fonseca, Felipe Paiva; Mesquita, Ricardo Alves; Gomez, Ricardo Santiago; Martínez-Flores, René; Delgado-Azañero, Wilson; Alves, Adriana Terezinha Neves Novellino; Lourenço, Simone de Queiroz Chaves; Coimbra, Carolina; Polignano, Giovanni Augusto Castanheira; Assunção Júnior, José Narciso Rosa; Souto, Giovanna Ribeiro; Souza, Paulo Eduardo Alencar; Horta, Martinho Campolina Rebello; González-Arriagada, Wilfredo Alejandro; Romañach, Mário José (Wiley, 2021)
    OBJECTIVE: To report the clinicopathologic features of acquired oral syphilis cases in South American countries. MATERIALS AND METHODS: Clinical data were retrospectively collected from the records of 18 oral diagnostic ...
  • Characterizing the syphilis epidemic among men who have sex with men in Lima, Peru to identify new treatment and control strategies 
    Deiss, Robert G.; León Sandoval, Segundo Ramos; Konda, KelikaA.; Brown, Brandon; Segura, Eddy R.; Galea, Jerome T.; Caceres Palacios, Carlos Fernando; Klausner, Jeffrey D. (BioMed Central, 2013)
    Background: Syphilis is an important sexually transmitted infection (STI) with serious public health consequences. Among men who have sex with men (MSM) in Lima, the prevalence and incidence are extraordinarily high. Current ...
  • Cytokine expression in Treponema pallidum infection 
    Kojima, N.; Siebert, J. C.; Maecker, H.; Rosenberg-Hasson, Y.; León Sandoval, Segundo Ramos; Vargas Rivera, Silver Keith; Konda, K. A.; Caceres Palacios, Carlos Fernando; Klausner, J. D. (BioMed Central, 2019)
    Background. Current syphilis tests cannot distinguish between active and past syphilis among patients with serofast rapid plasma reagin (RPR) titers. We investigated whether cytokine profiles might provide insight in the ...
  • Dual rapid test for HIV and syphilis: A laboratory evaluation of the diagnostic accuracy of the Standard Q HIV/Syphilis Combo Test 
    Bristow, Claire C.; Vargas Rivera, Silver Keith; Ramos Cordova, Lourdes B.; Qquellon Palacios, Luz Jazmín; Konda, Kelika A.; Klausner, Jeffrey D. (Elsevier, 2018)
    We evaluated the Standard Q HIV/Syphilis Combo Test (SD Biosensor, South Korea), a dual rapid test using stored sera (N = 400) in a laboratory setting in Lima, Peru. The sensitivity and specificity for HIV antibody detection ...
  • High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny 
    Lieberman, Nicole A. P.; Armstrong, Thaddeus D.; Chung, Benjamin; Pfalmer, Daniel; Hennelly, Christopher M.; Haynes, Austin; Romeis, Emily; Wang, Qian-Qiu; Zhang, Rui-Li; Kou, Cai-Xia; Ciccarese, Giulia; Conte, Ivano Dal; Cusini, Marco; Drago, Francesco; Nakayama, Shu-Ichi; Lee, Kenichi; Ohnishi, Makoto; Konda, Kelika A.; Vargas Rivera, Silver Keith; Eguiluz, Maria; Caceres Palacios, Carlos Fernando; Klausner, Jeffrey D.; Mitja, Oriol; Rompalo, Anne; Mulcahy, Fiona; Hook, Edward W. 3rd; Hoffman, Irving F.; Matoga, Mitch M.; Zheng, Heping; Yang, Bin; Lopez-Medina, Eduardo; Ramirez, Lady G; Radolf, Justin D.; Hawley, Kelly L.; Salazar, Juan C.; Lukehart, Sheila A.; Sena, Arlene C.; Parr, Jonathan B.; Giacani, Lorenzo; Greninger, Alexander L. (Frontiers Media, 2022)
    Sequencing of most Treponema pallidum genomes excludes repeat regions in tp0470 and the tp0433 gene, encoding the acidic repeat protein (arp). As a first step to understanding the evolution and function of these genes and ...
  • Impact of international laboratory partnerships on the performance of HIV/sexually transmitted infection testing in five resource-constrained countries 
    Gaydos, C.A.; Rizzo-Price, P.A.; Balakrishnan, P.; Mateta, P.; León Sandoval, Segundo Ramos; Verevochkin, S.; Yin, Y.P.; Quinn, T.C.; Strader, L.C.; Pequegnat, W. (SAGE Publications, 2011)
    To review a quality control and quality assurance (QC/QA) model established to ensure the validity and reliability of collection, storage and analysis of biological outcome data, and to promote good laboratory practices ...
  • Investigation of syphilis immunology and Treponema pallidum subsp. pallidum biology to improve clinical management and design a broadly protective vaccine: Study protocol 
    Osias, E.; Hung, P.; Giacani, L.; Stafylis, C.; Konda, K.A.; Vargas Rivera, Silver Keith; Reyes-Díaz, E.M.; Comulada, W.S.; Haake, D.A.; Haynes, A.M.; Caceres Palacios, Carlos Fernando; Klausner, J.D. (BioMed Central, 2020)
    Background: The syphilis epidemic continues to cause substantial morbidity and mortality worldwide, particularly in low- and middle-income countries, despite several recent disease control initiatives. Though our understanding ...
  • The molecular epidemiology of Treponema pallidum subspecies pallidum 
    Ma, Daphne Y.; Giacani, Lorenzo; Centurion-Lara, Arturo (CSIRO Publishing, 2015)
    Pathogens adapt and evolve in response to pressures exerted by host environments, leading to generation of genetically diverse variants. Treponema pallidum subspecies pallidum displays a substantial amount of interstrain ...
  • Non-pathogenic Borrelia burgdorferi expressing Treponema pallidum TprK and Tp0435 antigens as a novel approach to evaluate syphilis vaccine candidates 
    Parveen, N.; Fernandez, M.C.; Haynes, A.M.; Zhang, R.-L.; Godornes, B.C.; Centurion-Lara, A.; Giacani, L. (Elsevier, 2019)
    Background: Syphilis is resurgent in many developed countries and still prevalent in developing nations. Current and future control campaigns would benefit from the development of a vaccine, but although promising vaccine ...
  • Operations research study to implement HIV and syphilis point-of-care tests and assess client perceptions in a marginalised area of Lima, Peru 
    Flores, Elaine C.; Lluque, Maria E.; Chiappe Gutierrez, Marina Angelica; Lino, Rosabel; Bayer, Angela M. (SAGE Publications, 2014)
    In Peru, a significant proportion of people tested for HIV and syphilis do not receive timely results. Our objective was to assess the institutional feasibility of implementing simultaneous HIV/syphilis point-of-care tests ...
  • Syphilis 
    Peeling, Rosanna W.; Mabey, David; Chen, Xiang-Sheng; Garcia Funegra, Patricia Jannet (Elsevier, 2023)
    Syphilis is a sexually and vertically transmitted bacterial infection caused by the bacterium Treponema pallidum. Its prevalence is high in low-income and middle-income countries, and its incidence has increased in high-income ...
  • Transcription of TP0126, Treponema pallidum putative OmpW homolog, is regulated by the length of a homopolymeric guanosine repeat 
    Giacani, L.; Brandt, S.L.; Ke, W.; Reid, T.B.; Molini, B.J.; Iverson-Cabral, S.; Ciccarese, G.; Drago, F.; Lukehart, S.A.; Centurion-Lara, A. (American Society for Microbiology, 2015)
    An effective mechanism for introduction of phenotypic diversity within a bacterial population exploits changes in the length of repetitive DNA elements located within gene promoters. This phenomenon, known as phase variation, ...
  • Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum 
    Haynes, Austin M.; Fernandez, Mark; Romeis, Emily; Mitjà, Oriol; Konda, Kelika A.; Vargas Rivera, Silver Keith; Eguiluz, Maria; Caceres Palacios, Carlos Fernando; Klausner, Jeffrey D.; Giacani, Lorenzo (Public Library of Science, 2021)
    BACKGROUND: An effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis. Although the combination ...
  • WHO guidelines for HIV/STI prevention and care among MSM and transgender people: Implications for policy and practice 
    Cohen, Jenny; Lo, Ying-Ru; Caceres Palacios, Carlos Fernando; Klausner, Jeffrey D. (BMJ Publishing Group, 2013)
    Rates of sexually transmitted infections (STIs) in men who have sex with men (MSM) peaked in the late 1980s in the developed world and then declined and resurged in the late 1990s…

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