Universidad Peruana Cayetano Heredia

ListarArtículos en revistas indizadas por tema "normal human"

ListarArtículos en revistas indizadas por tema "normal human"

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  • Asymmetric dimethylarginine at sea level is a predictive marker of hypoxic pulmonary arterial hypertension at high altitude 
    Siques, Patricia; Brito, Julio; Schwedhelm, Edzard; Pena, Eduardo; León-Velarde, Fabiola; De La Cruz, Juan Jose; Boeger, Rainer H.; Hannemann, Juliane (Frontiers Media, 2019)
    Background: Prolonged exposure to altitude-associated chronic hypoxia (CH) may cause high-altitude pulmonary hypertension (HAPH). Chronic intermittent hypobaric hypoxia (CIH) occurs in individuals who commute between sea ...
  • A cross-sectional study of differences in 6-min walk distance in healthy adults residing at high altitude versus sea level 
    Caffrey, Deirdre; Miranda, J. Jaime; Gilman, Robert Hugh; Davila-Roman, Victor G.; Cabrera, Lilia; Dowling, Russell; Stewart, Talia; Bernabé Ortiz, Antonio; Wise, Robert; León-Velarde, Fabiola; Checkley, William; CRONICAS Cohort (BioMed Central, 2014)
    Background: We sought to determine if adult residents living at high altitude have developed sufficient adaptation to a hypoxic environment to match the functional capacity of a similar population at sea level. To test ...
  • Facial asymmetry and genetic ancestry in Latin American admixed populations 
    Quinto-Sánchez, Mirsha; Adhikari, K.; Acuña-Alonzo, V.; Cintas, C.; Silva De Cerqueira, C.C.; Ramallo, V.; Castillo, L.; Farrera, A.; Jaramillo, C.; Arias, W.; Fuentes, M.; Everardo, P.; De Avila, F.; Gomez-Valdés, J.; Hünemeier, T.; Gibbon, S.; Gallo López-Aliaga, Carla Maria; Poletti, Giovanni; Rosique, J.; Bortolini, M.C.; Canizales-Quinteros, S.; Rothhammer, F.; Bedoya, G.; Ruiz-Linares, A.; González-José, R. (Wiley, 2015)
    Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of ...
  • Genetic components of human pain sensitivity: A protocol for a genome-wide association study of experimental pain in healthy volunteers 
    Schmid, Annina B.; Adhikari, Kaustubh; Ramirez-Aristeguieta, Luis Miguel; Chacon-Duque, Juan-Camilo; Poletti, Giovanni; Gallo López-Aliaga, Carla Maria; Rothhammer, Francisco; Bedoya, Gabriel; Ruiz-Linares, Andres; Bennett, David L. (BMJ Publishing Group, 2019)
    INTRODUCTION: Pain constitutes a major component of the global burden of diseases. Recent studies suggest a strong genetic contribution to pain susceptibility and severity. Whereas most of the available evidence relies on ...
  • A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia 
    Adhikari, K.; Mendoza-Revilla, J.; Sohail, A.; Fuentes-Guajardo, M.; Lampert, J.; Chacón-Duque, J.C.; Hurtado, M.; Villegas, V.; Granja, V.; Acuña-Alonzo, V.; Jaramillo, C.; Arias, W.; Lozano, R.B.; Everardo, P.; Gómez-Valdés, J.; Villamil-Ramírez, H.; Silva de Cerqueira, C.C.; Hunemeier, T.; Ramallo, V.; Schuler-Faccini, L.; Salzano, F.M.; Gonzalez-José, R.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo López-Aliaga, Carla Maria; Poletti, G.; Bedoya, G.; Rothhammer, F.; Tobin, D.J.; Fumagalli, M.; Balding, D.; Ruiz-Linares, A. (Springer Nature, 2019)
    We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation ...
  • Impact of an Andean breakfast on biochemistry and immunochemistry laboratory tests: an evaluation on behalf COLABIOCLI WG-PRE-LATAM. 
    Bajaña, W.; Aranda, E.; Arredondo, M.E.; Brennan-Bourdon, L.M.; Campelo, M.D.; Espinoza, E.; Flores, S.; Ochoa, P.; Vega, V.; Varela, B.; Lima-Oliveira, G. (Croatian Society of Medical Biochemistry and Laboratory Medicine, 2019)
    Introduction: In Andean countries, specifically in Ecuador, a food transition in the population has been observed because of economic growth. The Working Group for Preanalytical Phase in Latin America (WG-PRE-LATAM) of the ...
  • Implications of the admixture process in skin color molecular assessment 
    Cerqueira, Caio Cesar Silva de; Hünemeier, Tábita; Gomez-Valdés, Jorge; Ramallo, Virgínia; Volasko-Krause, Carla Daiana; Barbosa, Ana Angélica Leal; Vargas-Pinilla, Pedro; Dornelles, Rodrigo Ciconet; Longo, Danaê; Rothhammer, Francisco; Bedoya, Gabriel; Canizales-Quinteros, Samuel; Acuña-Alonzo, Victor; Gallo López-Aliaga, Carla Maria; Poletti, Giovanni; González-José, Rolando; Salzano, Francisco Mauro; Callegari-Jacques, Sídia Maria; Schuler-Faccini, Lavínia; Ruiz-Linares, Andrés; Cátira Bortolini, Maria (Public Library of Science, 2014)
    The understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes ...
  • A multiple indicators multiple causes model of late-life depression in Latin American countries 
    Brailean, A.; Guerra Arteaga, Mariella; Chua, K.-C.; Prince, M.; Prina, M.A. (Elsevier, 2015)
    Background: The Euro-D depression scale consists of symptom clusters that may be differentially related to demographic and cognitive characteristics in older adults. This hypothesis needs further investigation and the role ...
  • Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: A randomized, placebo-controlled first-inhuman single-dose escalation study 
    An, G.; Murry, D.J.; Gajurel, K.; Bach, T.; Deye, G.; Stebounova, L.V.; Codd, E.E.; Horton, J.; Gonzalez Zariquiey, Armando Emiliano; García Lescano, Héctor Hugo; Ince, D.; Hodgson-Zingman, D.; Nomicos, E.Y.H.; Conrad, T.; Kennedy, J.; Jones, W.; Gilman, Robert Hugh; Winokur, P. (American Society for Microbiology, 2019)
    Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of ...
  • Use of open mobile mapping tool to assess human mobility traceability in rural offline populations with contrasting malaria dynamics 
    Carrasco Escobar, Gabriel; Castro, M.C.; Barboza, J.L.; Ruiz Cabrejos, Jorge; Llanos Cuentas, Elmer Alejandro; Vinetz, Joseph Michael; Gamboa Vilela, Dionicia Baziliza (PeerJ, 2019)
    Infectious disease dynamics are affected by human mobility more powerfully than previously thought, and thus reliable traceability data are essential. In rural riverine settings, lack of infrastructure and dense tree ...
  • Voriconazole as a first-line treatment against potentially pathogenic Acanthamoeba strains from Peru 
    Cabello Vílchez, Alfonso Martín; Martín-Navarro, C.M.; López-Arencibia, A.; Reyes-Batlle, M.; Sifaoui, I.; Valladares, B.; Piñero, J.E.; Lorenzo-Morales, J. (Springer Verlag, 2013)
    Pathogenic strains of Acanthamoeba genus are the causative agents of fatal granulomatous amoebic encephalitis and a serious sight-threatening infection of the eye known as Acanthamoeba keratitis. In a previous study, ...

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