ListarArtículos en revistas indizadas por tema "pyrazinamidase"

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Estimation of pyrazinamidase activity using a cell-free In vitro synthesis of pnca and its association with pyrazinamide susceptibility in Mycobacterium tuberculosis

Rueda, Daniel; Bernard, Christine; Gandy, Lucas; Capton, Estelle; Boudjelloul, Rachid; Brossier, Florence; Veziris, Nicolas; Zimic-Peralta, Mirko Juan; Sougakoff, Wladimir (Medknow Publications, 2018)

Background: The main mechanism of resistance to PZA in Mycobacterium tuberculosis relies on mutations on its pyrazinamidase/nicotinamidase. Recently, a rapid colorimetric test relying on the PCR-based in vitro-synthesized-PZase ...
Role of metal ions on the activity of Mycobacterium tuberculosis pyrazinamidase

Sheen Cortavarria, Patricia; Ferrer, P.; Gilman, Robert Hugh; Christiansen, G.; Moreno-Román, P.; Gutiérrez, A.H.; Sotelo, J.; Evangelista, W.; Fuentes, P.; Rueda, D.; Flores, M.; Olivera, P.; Solis, J.; Pesaresi, A.; Lamba, D.; Zimic-Peralta, Mirko Juan (American Society of Tropical Medicine and Hygiene, 2012)

Pyrazinamidase of Mycobacterium tuberculosis catalyzes the conversion of pyrazinamide to the active molecule pyrazinoic acid. Reduction of pyrazinamidase activity results in a level of pyrazinamide resistance. Previous ...

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