Universidad Peruana Cayetano Heredia

Association between household air pollution exposure and Chronic Obstructive Pulmonary Disease outcomes in 13 low- and middle-income country settings

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dc.contributor.author Siddharthan, Trishul
dc.contributor.author Grigsby, Matthew R.
dc.contributor.author Goodman, Dina
dc.contributor.author Chowdhury, Muhammad
dc.contributor.author Rubinstein, Adolfo
dc.contributor.author Irazola, Vilma
dc.contributor.author Gutierrez, Laura
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Alam, Dewan
dc.contributor.author Kirenga, Bruce
dc.contributor.author Jones, Rupert
dc.contributor.author van Gemert, Frederick
dc.contributor.author Wise, Robert A.
dc.contributor.author Checkley, William
dc.date.accessioned 2018-11-30T02:09:30Z
dc.date.available 2018-11-30T02:09:30Z
dc.date.issued 2018
dc.identifier.uri https://hdl.handle.net/20.500.12866/4005
dc.description.abstract RATIONALE: Forty percent of households worldwide burn biomass fuels for energy, which may be the most important contributor to household air pollution. OBJECTIVES: To examine the association between household air pollution exposure and chronic obstructive pulmonary disease (COPD) outcomes in 13 resource-poor settings. METHODS: We analyzed data from 12,396 adult participants living in 13 resource-poor, population-based settings. Household air pollution exposure was defined as using biomass materials as the primary fuel source in the home. We used multivariable regressions to assess the relationship between household air pollution exposure and COPD outcomes, evaluated for interactions, and conducted sensitivity analyses to test the robustness of our findings. MEASUREMENTS AND MAIN RESULTS: Average age was 54.9 years (44.2-59.6 yr across settings), 48.5% were women (38.3-54.5%), prevalence of household air pollution exposure was 38% (0.5-99.6%), and 8.8% (1.7-15.5%) had COPD. Participants with household air pollution exposure were 41% more likely to have COPD (adjusted odds ratio, 1.41; 95% confidence interval, 1.18-1.68) than those without the exposure, and 13.5% (6.4-20.6%) of COPD prevalence may be caused by household air pollution exposure, compared with 12.4% caused by cigarette smoking. The association between household air pollution exposure and COPD was stronger in women (1.70; 1.24-2.32) than in men (1.21; 0.92-1.58). CONCLUSIONS: Household air pollution exposure was associated with a higher prevalence of COPD, particularly among women, and it is likely a leading population-attributable risk factor for COPD in resource-poor settings. en_US
dc.language.iso eng
dc.publisher American Thoracic Society
dc.relation.ispartofseries American Journal of Respiratory and Critical Care Medicine
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject COPD en_US
dc.subject air pollution en_US
dc.subject biomass en_US
dc.subject indoor/adverse effects en_US
dc.title Association between household air pollution exposure and Chronic Obstructive Pulmonary Disease outcomes in 13 low- and middle-income country settings en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1164/rccm.201709-1861OC
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.07
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.08
dc.relation.issn 1535-4970


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