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Laboratory Diagnosis of Neurocysticercosis (Taenia solium)

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dc.contributor.author García Lescano, Héctor Hugo
dc.contributor.author O'Neal, Seth E.
dc.contributor.author Noh, John
dc.contributor.author Handali, Sukwan
dc.contributor.author Cysticercosis Working Group in Peru
dc.date.accessioned 2018-11-30T17:17:14Z
dc.date.available 2018-11-30T17:17:14Z
dc.date.issued 2018
dc.identifier.uri https://hdl.handle.net/20.500.12866/4109
dc.description.abstract Neurocysticercosis accounts for approximately 30% of all epilepsy cases in most developing countries. The immunodiagnosis of cysticercosis is complex and strongly influenced by the course of infection, the disease burden, the cyst location, and the immune response of the host. The main approach to immunodiagnosis should thus be to evaluate whether the serological results are consistent with the diagnosis suggested by imaging. Antibody detection is performed using lentil lectin-purified parasite antigens in an enzyme-linked immunoelectrotransfer blot format, while antigen detection uses a monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA). Promising new assay configurations have been developed for the detection of both antibody and antigen, including assays based on synthetic or recombinant antigens that may reduce costs and improve assay reproducibility and multiplex bead-based assays that may provide simultaneous quantitative results for several target antigens or antibodies. en_US
dc.language.iso eng
dc.publisher American Society for Microbiology
dc.relation.ispartofseries Journal of Clinical Microbiology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Peru en_US
dc.subject Taenia solium en_US
dc.subject neurocysticercosis en_US
dc.subject antibody en_US
dc.subject antigen en_US
dc.subject cysticercosis en_US
dc.subject EITB en_US
dc.subject ELISA en_US
dc.subject Western blot en_US
dc.title Laboratory Diagnosis of Neurocysticercosis (Taenia solium) en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1128/JCM.00424-18
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.01
dc.relation.issn 1098-660X


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