Laboratory Diagnosis of Neurocysticercosis (Taenia solium)

Handali, Sukwan; Noh, John; García Lescano, Héctor Hugo; O'Neal, Seth E.; Cysticercosis Working Group in Peru

dc.contributor.author	García Lescano, Héctor Hugo
dc.contributor.author	O'Neal, Seth E.
dc.contributor.author	Noh, John
dc.contributor.author	Handali, Sukwan
dc.contributor.author	Cysticercosis Working Group in Peru
dc.date.accessioned	2018-11-30T17:17:14Z
dc.date.available	2018-11-30T17:17:14Z
dc.date.issued	2018
dc.identifier.uri	https://hdl.handle.net/20.500.12866/4109
dc.description.abstract	Neurocysticercosis accounts for approximately 30% of all epilepsy cases in most developing countries. The immunodiagnosis of cysticercosis is complex and strongly influenced by the course of infection, the disease burden, the cyst location, and the immune response of the host. The main approach to immunodiagnosis should thus be to evaluate whether the serological results are consistent with the diagnosis suggested by imaging. Antibody detection is performed using lentil lectin-purified parasite antigens in an enzyme-linked immunoelectrotransfer blot format, while antigen detection uses a monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA). Promising new assay configurations have been developed for the detection of both antibody and antigen, including assays based on synthetic or recombinant antigens that may reduce costs and improve assay reproducibility and multiplex bead-based assays that may provide simultaneous quantitative results for several target antigens or antibodies.	en_US
dc.language.iso	eng
dc.publisher	American Society for Microbiology
dc.relation.ispartofseries	Journal of Clinical Microbiology
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Peru	en_US
dc.subject	Taenia solium	en_US
dc.subject	neurocysticercosis	en_US
dc.subject	antibody	en_US
dc.subject	antigen	en_US
dc.subject	cysticercosis	en_US
dc.subject	EITB	en_US
dc.subject	ELISA	en_US
dc.subject	Western blot	en_US
dc.title	Laboratory Diagnosis of Neurocysticercosis (Taenia solium)	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1128/JCM.00424-18
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#1.06.01
dc.relation.issn	1098-660X