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Improved tools and strategies for the prevention and control of arboviral diseases: A research-to-policy forum

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dc.contributor.author Olliaro, Piero
dc.contributor.author Fouque, Florence
dc.contributor.author Kroeger, Axel
dc.contributor.author Bowman, Leigh
dc.contributor.author Velayudhan, Raman
dc.contributor.author Santelli, Ana Carolina
dc.contributor.author Garcia, Diego
dc.contributor.author Skewes Ramm, Ronald
dc.contributor.author Sulaiman, Lokman H.
dc.contributor.author Sanchez Tejeda, Gustavo
dc.contributor.author Correa Morales, Fabián
dc.contributor.author Gozzer Infante, Ernesto Eugenio
dc.contributor.author Basso Garrido, César
dc.contributor.author Chan Quang, Luong
dc.contributor.author Gutierrez, Gamaliel
dc.contributor.author Yadon, Zaida E.
dc.contributor.author Runge-Ranzinger, Silvia
dc.date.accessioned 2018-12-03T17:02:50Z
dc.date.available 2018-12-03T17:02:50Z
dc.date.issued 2018
dc.identifier.uri https://hdl.handle.net/20.500.12866/4302
dc.description.abstract BACKGROUND: Research has been conducted on interventions to control dengue transmission and respond to outbreaks. A summary of the available evidence will help inform disease control policy decisions and research directions, both for dengue and, more broadly, for all Aedes-borne arboviral diseases. METHOD: A research-to-policy forum was convened by TDR, the Special Programme for Research and Training in Tropical Diseases, with researchers and representatives from ministries of health, in order to review research findings and discuss their implications for policy and research. RESULTS: The participants reviewed findings of research supported by TDR and others. Surveillance and early outbreak warning. Systematic reviews and country studies identify the critical characteristics that an alert system should have to document trends reliably and trigger timely responses (i.e., early enough to prevent the epidemic spread of the virus) to dengue outbreaks. A range of variables that, according to the literature, either indicate risk of forthcoming dengue transmission or predict dengue outbreaks were tested and some of them could be successfully applied in an Early Warning and Response System (EWARS). Entomological surveillance and vector management. A summary of the published literature shows that controlling Aedes vectors requires complex interventions and points to the need for more rigorous, standardised study designs, with disease reduction as the primary outcome to be measured. House screening and targeted vector interventions are promising vector management approaches. Sampling vector populations, both for surveillance purposes and evaluation of control activities, is usually conducted in an unsystematic way, limiting the potentials of entomological surveillance for outbreak prediction. Combining outbreak alert and improved approaches of vector management will help to overcome the present uncertainties about major risk groups or areas where outbreak response should be initiated and where resources for vector management should be allocated during the interepidemic period. CONCLUSIONS: The Forum concluded that the evidence collected can inform policy decisions, but also that important research gaps have yet to be filled. en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS Neglected Tropical Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Humans en_US
dc.subject Animals en_US
dc.subject Risk Factors en_US
dc.subject Aedes en_US
dc.subject Arbovirus Infections en_US
dc.subject Dengue en_US
dc.subject Disease Outbreaks en_US
dc.subject Global Health en_US
dc.subject Health Planning en_US
dc.subject Insect Vectors en_US
dc.subject Population Surveillance en_US
dc.subject Research Design en_US
dc.subject Risk Assessment en_US
dc.title Improved tools and strategies for the prevention and control of arboviral diseases: A research-to-policy forum en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pntd.0005967
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1935-2735


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