First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR)

Cardoso Linhares, Fernanda Athayde; Levy, Roger A.; Garcia de la Torre, Ignacio; Reyes Llerena, Gil; Ugolini-Lopes, Michelle R.; Amigo, Mary-Carmen; Robaina Sevrini, Ricardo; Amezcua-Guerra, Luis M.; Haye Salinas, Maria Jezabel; Da Silva, Nilzio A.; Cardiel, Mario H.; Fuentes-Silva, Yurilis J.; Catoggio, Luis J.; Pons-Estel, Guillermo J.; Herrera Uribe, Sebastián; Tavares Brenol, João C.; Ugarte Gil, Manuel Francisco; Montandon de Oliveira e Silva, Ana Carolina; Xavier, Ricardo M.; Cairoli, Ernesto; Criniti, Juan M.; Alarcón, Graciela S.; Gerling, Cristian; Izcovich, Ariel; Massardo, Loreto; Barile-Fabris, Leonor A.; García, Mercedes A.; Scolnik, Marina; Torres Dos Reis Neto, Edgard; Portela Hernández, Margarita; Eraso Garnica, Ruth M.; Gamboa-Cárdenas, Rocio V.; Mora-Trujillo, Claudia S.; González Naranjo, Luis A.; Montúfar Guardado, Rubén A.; Costa Seguro, Luciana Parente; Chacón-Díaz, Rosa; Borba, Eduardo F.; Bonfa, Eloisa; Alvarellos, Alejandro J.; Pera, Mariana A.; Sato, Emilia Inoue; Gómez-Martín, Diana; Lavras Costallat, Lilian T.; Drenkard, Cristina; Babini, Alejandra; Retamozo, Soledad; Rosario, Violeta; Molina, José Fernando; Cieza, Jorge; Muñoz-Louis, Roberto; Monticielo, Odirlei A.; Iglesias Gamarra, Antonio J.; Pineda, Carlos; Acosta Colman, Maria Isabel; Aquino, Alicia M.; Conti, Silvana M.; Arturi, Valeria; Espada, Graciela; Neira, Oscar; Quintana, Rosana M.; Appenzeller, Simone; Gervasoni, Viviana L.; Sattler, María E.; Scherbarth, Hugo R.; Cavalcanti, Fernando; Soriano, Enrique R.; Popoff, Federico; Danza, Alvaro; Alba Moreyra, Paula B.; Burgos, Paula I.; Silveira, Luis H.; Gordon, Sergio; Fragoso-Loyo, Hilda; Silva, Clóvis A.; Saurit, Verónica; Galarza-Maldonado, Claudio M.; Llanos, Carolina; Acevedo Vásquez, Eduardo M.; Duarte, Margarita; Pons-Estel, Bernardo A.; Vargas Peña, Andrea; Berbotto, Guillermo A.; Collado, María Victoria; Gobbi, Carla A.; Gómez-Puerta, José A.; Guibert-Toledano, Marlene; García Valladares, Ignacio; Orozco, María Celeste; Vásquez, Gloria; Sarano, Judith; Betancur, Graciela V.; González Bello, Yelitza C.; Cavalcanti, André; Savio, Verónica

dc.contributor.author	Pons-Estel, Bernardo A.
dc.contributor.author	Bonfa, Eloisa
dc.contributor.author	Soriano, Enrique R.
dc.contributor.author	Cardiel, Mario H.
dc.contributor.author	Izcovich, Ariel
dc.contributor.author	Popoff, Federico
dc.contributor.author	Criniti, Juan M.
dc.contributor.author	Vásquez, Gloria
dc.contributor.author	Massardo, Loreto
dc.contributor.author	Duarte, Margarita
dc.contributor.author	Barile-Fabris, Leonor A.
dc.contributor.author	García, Mercedes A.
dc.contributor.author	Amigo, Mary-Carmen
dc.contributor.author	Espada, Graciela
dc.contributor.author	Catoggio, Luis J.
dc.contributor.author	Sato, Emilia Inoue
dc.contributor.author	Levy, Roger A.
dc.contributor.author	Acevedo Vásquez, Eduardo M.
dc.contributor.author	Chacón-Díaz, Rosa
dc.contributor.author	Galarza-Maldonado, Claudio M.
dc.contributor.author	Iglesias Gamarra, Antonio J.
dc.contributor.author	Molina, José Fernando
dc.contributor.author	Neira, Oscar
dc.contributor.author	Silva, Clóvis A.
dc.contributor.author	Vargas Peña, Andrea
dc.contributor.author	Gómez-Puerta, José A.
dc.contributor.author	Scolnik, Marina
dc.contributor.author	Pons-Estel, Guillermo J.
dc.contributor.author	Ugolini-Lopes, Michelle R.
dc.contributor.author	Savio, Verónica
dc.contributor.author	Drenkard, Cristina
dc.contributor.author	Alvarellos, Alejandro J.
dc.contributor.author	Ugarte Gil, Manuel Francisco
dc.contributor.author	Babini, Alejandra
dc.contributor.author	Cavalcanti, André
dc.contributor.author	Cardoso Linhares, Fernanda Athayde
dc.contributor.author	Haye Salinas, Maria Jezabel
dc.contributor.author	Fuentes-Silva, Yurilis J.
dc.contributor.author	Montandon de Oliveira e Silva, Ana Carolina
dc.contributor.author	Eraso Garnica, Ruth M.
dc.contributor.author	Herrera Uribe, Sebastián
dc.contributor.author	Gómez-Martín, Diana
dc.contributor.author	Robaina Sevrini, Ricardo
dc.contributor.author	Quintana, Rosana M.
dc.contributor.author	Gordon, Sergio
dc.contributor.author	Fragoso-Loyo, Hilda
dc.contributor.author	Rosario, Violeta
dc.contributor.author	Saurit, Verónica
dc.contributor.author	Appenzeller, Simone
dc.contributor.author	Torres Dos Reis Neto, Edgard
dc.contributor.author	Cieza, Jorge
dc.contributor.author	González Naranjo, Luis A.
dc.contributor.author	González Bello, Yelitza C.
dc.contributor.author	Collado, María Victoria
dc.contributor.author	Sarano, Judith
dc.contributor.author	Retamozo, Soledad
dc.contributor.author	Sattler, María E.
dc.contributor.author	Gamboa-Cárdenas, Rocio V.
dc.contributor.author	Cairoli, Ernesto
dc.contributor.author	Conti, Silvana M.
dc.contributor.author	Amezcua-Guerra, Luis M.
dc.contributor.author	Silveira, Luis H.
dc.contributor.author	Borba, Eduardo F.
dc.contributor.author	Pera, Mariana A.
dc.contributor.author	Alba Moreyra, Paula B.
dc.contributor.author	Arturi, Valeria
dc.contributor.author	Berbotto, Guillermo A.
dc.contributor.author	Gerling, Cristian
dc.contributor.author	Gobbi, Carla A.
dc.contributor.author	Gervasoni, Viviana L.
dc.contributor.author	Scherbarth, Hugo R.
dc.contributor.author	Tavares Brenol, João C.
dc.contributor.author	Cavalcanti, Fernando
dc.contributor.author	Lavras Costallat, Lilian T.
dc.contributor.author	Da Silva, Nilzio A.
dc.contributor.author	Monticielo, Odirlei A.
dc.contributor.author	Costa Seguro, Luciana Parente
dc.contributor.author	Xavier, Ricardo M.
dc.contributor.author	Llanos, Carolina
dc.contributor.author	Montúfar Guardado, Rubén A.
dc.contributor.author	Garcia de la Torre, Ignacio
dc.contributor.author	Pineda, Carlos
dc.contributor.author	Portela Hernández, Margarita
dc.contributor.author	Danza, Alvaro
dc.contributor.author	Guibert-Toledano, Marlene
dc.contributor.author	Reyes Llerena, Gil
dc.contributor.author	Acosta Colman, Maria Isabel
dc.contributor.author	Aquino, Alicia M.
dc.contributor.author	Mora-Trujillo, Claudia S.
dc.contributor.author	Muñoz-Louis, Roberto
dc.contributor.author	García Valladares, Ignacio
dc.contributor.author	Orozco, María Celeste
dc.contributor.author	Burgos, Paula I.
dc.contributor.author	Betancur, Graciela V.
dc.contributor.author	Alarcón, Graciela S.
dc.date.accessioned	2018-12-03T17:02:50Z
dc.date.available	2018-12-03T17:02:50Z
dc.date.issued	2018
dc.identifier.uri	https://hdl.handle.net/20.500.12866/4305
dc.description.abstract	Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therapeutic guidelines are developed. The objective of the study is to develop clinical practice guidelines for Latin American patients with lupus. Two independent teams (rheumatologists with experience in lupus management and methodologists) had an initial meeting in Panama City, Panama, in April 2016. They selected a list of questions for the clinical problems most commonly seen in Latin American patients with SLE. These were addressed with the best available evidence and summarised in a standardised format following the Grading of Recommendations Assessment, Development and Evaluation approach. All preliminary findings were discussed in a second face-to-face meeting in Washington, DC, in November 2016. As a result, nine organ/system sections are presented with the main findings; an 'overarching' treatment approach was added. Special emphasis was made on regional implementation issues. Best pharmacologic options were examined for musculoskeletal, mucocutaneous, kidney, cardiac, pulmonary, neuropsychiatric, haematological manifestations and the antiphospholipid syndrome. The roles of main therapeutic options (ie, glucocorticoids, antimalarials, immunosuppressant agents, therapeutic plasma exchange, belimumab, rituximab, abatacept, low-dose aspirin and anticoagulants) were summarised in each section. In all cases, benefits and harms, certainty of the evidence, values and preferences, feasibility, acceptability and equity issues were considered to produce a recommendation with special focus on ethnic and socioeconomic aspects. Guidelines for Latin American patients with lupus have been developed and could be used in similar settings.	en_US
dc.language.iso	eng
dc.publisher	BMJ Publishing Group
dc.relation.ispartofseries	Annals of the Rheumatic Diseases
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	treatment	en_US
dc.subject	systemic lupus erythematosus	en_US
dc.subject	lupus nephritis	en_US
dc.title	First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR)	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1136/annrheumdis-2018-213512
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.02.17
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.01.03
dc.relation.issn	1468-2060