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First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR)

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dc.contributor.author Pons-Estel, Bernardo A.
dc.contributor.author Bonfa, Eloisa
dc.contributor.author Soriano, Enrique R.
dc.contributor.author Cardiel, Mario H.
dc.contributor.author Izcovich, Ariel
dc.contributor.author Popoff, Federico
dc.contributor.author Criniti, Juan M.
dc.contributor.author Vásquez, Gloria
dc.contributor.author Massardo, Loreto
dc.contributor.author Duarte, Margarita
dc.contributor.author Barile-Fabris, Leonor A.
dc.contributor.author García, Mercedes A.
dc.contributor.author Amigo, Mary-Carmen
dc.contributor.author Espada, Graciela
dc.contributor.author Catoggio, Luis J.
dc.contributor.author Sato, Emilia Inoue
dc.contributor.author Levy, Roger A.
dc.contributor.author Acevedo Vásquez, Eduardo M.
dc.contributor.author Chacón-Díaz, Rosa
dc.contributor.author Galarza-Maldonado, Claudio M.
dc.contributor.author Iglesias Gamarra, Antonio J.
dc.contributor.author Molina, José Fernando
dc.contributor.author Neira, Oscar
dc.contributor.author Silva, Clóvis A.
dc.contributor.author Vargas Peña, Andrea
dc.contributor.author Gómez-Puerta, José A.
dc.contributor.author Scolnik, Marina
dc.contributor.author Pons-Estel, Guillermo J.
dc.contributor.author Ugolini-Lopes, Michelle R.
dc.contributor.author Savio, Verónica
dc.contributor.author Drenkard, Cristina
dc.contributor.author Alvarellos, Alejandro J.
dc.contributor.author Ugarte Gil, Manuel Francisco
dc.contributor.author Babini, Alejandra
dc.contributor.author Cavalcanti, André
dc.contributor.author Cardoso Linhares, Fernanda Athayde
dc.contributor.author Haye Salinas, Maria Jezabel
dc.contributor.author Fuentes-Silva, Yurilis J.
dc.contributor.author Montandon de Oliveira e Silva, Ana Carolina
dc.contributor.author Eraso Garnica, Ruth M.
dc.contributor.author Herrera Uribe, Sebastián
dc.contributor.author Gómez-Martín, Diana
dc.contributor.author Robaina Sevrini, Ricardo
dc.contributor.author Quintana, Rosana M.
dc.contributor.author Gordon, Sergio
dc.contributor.author Fragoso-Loyo, Hilda
dc.contributor.author Rosario, Violeta
dc.contributor.author Saurit, Verónica
dc.contributor.author Appenzeller, Simone
dc.contributor.author Torres Dos Reis Neto, Edgard
dc.contributor.author Cieza, Jorge
dc.contributor.author González Naranjo, Luis A.
dc.contributor.author González Bello, Yelitza C.
dc.contributor.author Collado, María Victoria
dc.contributor.author Sarano, Judith
dc.contributor.author Retamozo, Soledad
dc.contributor.author Sattler, María E.
dc.contributor.author Gamboa-Cárdenas, Rocio V.
dc.contributor.author Cairoli, Ernesto
dc.contributor.author Conti, Silvana M.
dc.contributor.author Amezcua-Guerra, Luis M.
dc.contributor.author Silveira, Luis H.
dc.contributor.author Borba, Eduardo F.
dc.contributor.author Pera, Mariana A.
dc.contributor.author Alba Moreyra, Paula B.
dc.contributor.author Arturi, Valeria
dc.contributor.author Berbotto, Guillermo A.
dc.contributor.author Gerling, Cristian
dc.contributor.author Gobbi, Carla A.
dc.contributor.author Gervasoni, Viviana L.
dc.contributor.author Scherbarth, Hugo R.
dc.contributor.author Tavares Brenol, João C.
dc.contributor.author Cavalcanti, Fernando
dc.contributor.author Lavras Costallat, Lilian T.
dc.contributor.author Da Silva, Nilzio A.
dc.contributor.author Monticielo, Odirlei A.
dc.contributor.author Costa Seguro, Luciana Parente
dc.contributor.author Xavier, Ricardo M.
dc.contributor.author Llanos, Carolina
dc.contributor.author Montúfar Guardado, Rubén A.
dc.contributor.author Garcia de la Torre, Ignacio
dc.contributor.author Pineda, Carlos
dc.contributor.author Portela Hernández, Margarita
dc.contributor.author Danza, Alvaro
dc.contributor.author Guibert-Toledano, Marlene
dc.contributor.author Reyes Llerena, Gil
dc.contributor.author Acosta Colman, Maria Isabel
dc.contributor.author Aquino, Alicia M.
dc.contributor.author Mora-Trujillo, Claudia S.
dc.contributor.author Muñoz-Louis, Roberto
dc.contributor.author García Valladares, Ignacio
dc.contributor.author Orozco, María Celeste
dc.contributor.author Burgos, Paula I.
dc.contributor.author Betancur, Graciela V.
dc.contributor.author Alarcón, Graciela S.
dc.date.accessioned 2018-12-03T17:02:50Z
dc.date.available 2018-12-03T17:02:50Z
dc.date.issued 2018
dc.identifier.uri https://hdl.handle.net/20.500.12866/4305
dc.description.abstract Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therapeutic guidelines are developed. The objective of the study is to develop clinical practice guidelines for Latin American patients with lupus. Two independent teams (rheumatologists with experience in lupus management and methodologists) had an initial meeting in Panama City, Panama, in April 2016. They selected a list of questions for the clinical problems most commonly seen in Latin American patients with SLE. These were addressed with the best available evidence and summarised in a standardised format following the Grading of Recommendations Assessment, Development and Evaluation approach. All preliminary findings were discussed in a second face-to-face meeting in Washington, DC, in November 2016. As a result, nine organ/system sections are presented with the main findings; an 'overarching' treatment approach was added. Special emphasis was made on regional implementation issues. Best pharmacologic options were examined for musculoskeletal, mucocutaneous, kidney, cardiac, pulmonary, neuropsychiatric, haematological manifestations and the antiphospholipid syndrome. The roles of main therapeutic options (ie, glucocorticoids, antimalarials, immunosuppressant agents, therapeutic plasma exchange, belimumab, rituximab, abatacept, low-dose aspirin and anticoagulants) were summarised in each section. In all cases, benefits and harms, certainty of the evidence, values and preferences, feasibility, acceptability and equity issues were considered to produce a recommendation with special focus on ethnic and socioeconomic aspects. Guidelines for Latin American patients with lupus have been developed and could be used in similar settings. en_US
dc.language.iso eng
dc.publisher BMJ Publishing Group
dc.relation.ispartofseries Annals of the Rheumatic Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject treatment en_US
dc.subject systemic lupus erythematosus en_US
dc.subject lupus nephritis en_US
dc.title First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR) en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1136/annrheumdis-2018-213512
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.17
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.03
dc.relation.issn 1468-2060

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