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Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru

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dc.contributor.author Taype-Rondan, Alvaro
dc.contributor.author Abbs, Elizabeth Sarah
dc.contributor.author Lazo Porras, María de los Ángeles
dc.contributor.author Checkley, William
dc.contributor.author Gilman, Robert Hugh
dc.contributor.author Smeeth, Liam
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Bernabé Ortiz, Antonio
dc.date.accessioned 2019-01-25T15:02:18Z
dc.date.available 2019-01-25T15:02:18Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4606
dc.description.abstract PURPOSE: To evaluate the role of urbanization as an effect modifier for the association between specific chronic conditions and number of conditions with health-related quality of life (QOL). METHODS: We analyzed cross-sectional data from the CRONICAS Cohort Study conducted in Lima (highly urbanized), Tumbes (semi-urban), as well as rural and urban sites in Puno. Exposures of interest were chronic bronchitis, depressive mood, hypertension, type 2 diabetes, and a composite variable aggregating the number of chronic conditions (the four exposures plus heart disease and stroke). QOL outcomes were assessed with EuroQol's EQ-5D visual analogue scale (EQ-VAS). We fitted linear regressions with robust variance to evaluate the associations of interest. Study site was assessed as a potential effect modifier using the likelihood-ratio (LR) test. RESULTS: We evaluated data on 2433 subjects: 51.3% were female, mean age was 57.2 years. Study site was found to be an effect modifier only for the association between depressive mood and EQ-VAS score (LR test p < 0.001). Compared to those without depressive mood, participants with depressive mood scored -13.7 points on the EQ-VAS in Lima, -7.9 in urban Puno, -11.0 in semi-urban Tumbes, and -2.7 in rural Puno. Study site was not found to be an effect modifier for the association between the number of chronic conditions and EQ-VAS (LR test p = 0.64). CONCLUSION: The impact of depressive mood on EQ-VAS was larger in urban than in rural sites, while site was not an effect modifier for the remaining associations. en_US
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartofseries Quality of Life Research
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Burden of disease en_US
dc.subject Depressive mood en_US
dc.subject Health-related quality of life en_US
dc.subject Multiple chronic conditions en_US
dc.subject Adult en_US
dc.subject Chronic Disease en_US
dc.subject Cohort Studies en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Disease/ethnology en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Peru en_US
dc.subject Quality of Life/psychology en_US
dc.subject Surveys and Questionnaires en_US
dc.subject Urbanization/trends en_US
dc.title Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1007/s11136-017-1649-7
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1573-2649


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