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Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru

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dc.contributor.author Taype-Rondan, Alvaro
dc.contributor.author Abbs, Elizabeth Sarah
dc.contributor.author Lazo-Porras, Maria
dc.contributor.author Checkley, William
dc.contributor.author Gilman, Robert H.
dc.contributor.author Smeeth, Liam
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Bernabe-Ortiz, Antonio
dc.date.accessioned 2019-01-25T15:02:18Z
dc.date.available 2019-01-25T15:02:18Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4606
dc.description.abstract PURPOSE: To evaluate the role of urbanization as an effect modifier for the association between specific chronic conditions and number of conditions with health-related quality of life (QOL). METHODS: We analyzed cross-sectional data from the CRONICAS Cohort Study conducted in Lima (highly urbanized), Tumbes (semi-urban), as well as rural and urban sites in Puno. Exposures of interest were chronic bronchitis, depressive mood, hypertension, type 2 diabetes, and a composite variable aggregating the number of chronic conditions (the four exposures plus heart disease and stroke). QOL outcomes were assessed with EuroQol's EQ-5D visual analogue scale (EQ-VAS). We fitted linear regressions with robust variance to evaluate the associations of interest. Study site was assessed as a potential effect modifier using the likelihood-ratio (LR) test. RESULTS: We evaluated data on 2433 subjects: 51.3% were female, mean age was 57.2 years. Study site was found to be an effect modifier only for the association between depressive mood and EQ-VAS score (LR test p < 0.001). Compared to those without depressive mood, participants with depressive mood scored -13.7 points on the EQ-VAS in Lima, -7.9 in urban Puno, -11.0 in semi-urban Tumbes, and -2.7 in rural Puno. Study site was not found to be an effect modifier for the association between the number of chronic conditions and EQ-VAS (LR test p = 0.64). CONCLUSION: The impact of depressive mood on EQ-VAS was larger in urban than in rural sites, while site was not an effect modifier for the remaining associations. en_US
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartof urn:issn:1573-2649
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Burden of disease en_US
dc.subject Depressive mood en_US
dc.subject Health-related quality of life en_US
dc.subject Multiple chronic conditions en_US
dc.subject Adult en_US
dc.subject Chronic Disease en_US
dc.subject Cohort Studies en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Disease/ethnology en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Peru en_US
dc.subject Quality of Life/psychology en_US
dc.subject Surveys and Questionnaires en_US
dc.subject Urbanization/trends en_US
dc.title Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1007/s11136-017-1649-7


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