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Evaluation of the efficacy, safety and acceptability of a fish protein isolate in the nutrition of children under 36 months of age

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dc.contributor.author Ochoa Woodell, Theresa Jean
dc.contributor.author Baiocchi, Nelly
dc.contributor.author Valdiviezo Villacorta, Gladys Victoria
dc.contributor.author Bullon, Vanessa
dc.contributor.author Campos, Miguel
dc.contributor.author Llanos Cuentas, Elmer Alejandro
dc.date.accessioned 2019-01-25T15:18:34Z
dc.date.available 2019-01-25T15:18:34Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4648
dc.description.abstract OBJECTIVE: To determine the effect of a fish protein isolate (FPi), administered over 6 months, on the growth of children aged 6-36 months, measured by Z-scores of height-for-age (HAZ) and weight-for-height (WHZ), compared with the standard meal without FPi; and to determine the safety and acceptability of FPi daily consumption. DESIGN: Cluster-randomized community-based controlled trial. For 6 months, the centres received either FPi replacing 50 % of total proteins in the diet or standard protein. HAZ and WHZ were used to determine the effect on growth. Acceptability was determined by daily consumption, measured by weighing the servings before and after consumption. SETTING: Day care centres and community nutritional centres in northern Lima, Peru. SUBJECTS: Children (n 441) aged 6-36 months. RESULTS: Four centres were randomized to the intervention with FPi, five centres were randomized to the standard control diet. More than 36 900 meals were prepared and administered in a supervised manner. Both groups received the same amounts of energy and proteins daily (proteins about 12-15 % of total energy). Growth of children who received the FPi diet was similar to that of children with the standard diet. Consumption was similar in the FPi and control groups (70 v. 80 % of amount offered, respectively). The protein was safe and well tolerated. No adverse events were reported. However, the cost of the intervention with FPi was 20-40 % lower v. the standard diet with animal protein derived from beef, chicken, eggs or liver. CONCLUSIONS: The FPi was well accepted and there was no significant difference in growth between both groups. FPi is a potential source of animal protein at lower cost. en_US
dc.language.iso eng
dc.publisher Cambridge University Press
dc.relation.ispartofseries Public Health Nutrition
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Diet en_US
dc.subject Dietary Supplements en_US
dc.subject Body Height en_US
dc.subject Body Weight en_US
dc.subject Child Day Care Centers en_US
dc.subject Child, Preschool en_US
dc.subject Children en_US
dc.subject Cluster Analysis en_US
dc.subject Dietary protein en_US
dc.subject Female en_US
dc.subject Fish protein isolate en_US
dc.subject Fish Proteins/administration & dosage en_US
dc.subject Follow-Up Studies en_US
dc.subject Food consumption en_US
dc.subject Humans en_US
dc.subject Infant en_US
dc.subject Infant Nutritional Physiological Phenomena en_US
dc.subject Male en_US
dc.subject Malnutrition en_US
dc.subject Nutritional Status en_US
dc.subject Peru en_US
dc.subject Single-Blind Method en_US
dc.subject Treatment Outcome en_US
dc.title Evaluation of the efficacy, safety and acceptability of a fish protein isolate in the nutrition of children under 36 months of age en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1017/S136898001700163X
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.04
dc.relation.issn 1475-2727

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