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Infección por Cystoisospora belli en pacientes con VIH: análisis de casos con diferente evolución clínica

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dc.contributor.author Silva Díaz, Heber
dc.contributor.author Fernández Valverde, Darwin
dc.contributor.author Hernández Córdova, Gustavo
dc.contributor.author Failoc Rojas, Virgilio E.
dc.date.accessioned 2019-01-25T15:18:37Z
dc.date.available 2019-01-25T15:18:37Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4679
dc.description.abstract INTRODUCTION: Cystoisospora belli infection is one of the most important causes of watery diarrhea in patients with HIV and causes high rates of morbidity and mortality. METHODS: A retrospective study was conducted in patients with HIV and diarrhea by C. belli. Clinical and laboratory characteristics were collected by analyzing clinical records. RESULTS: Four had recurrent diarrhea despite receiving secondary prophylaxis with cotrimoxazole and specific treatment, two of which had a good viral and immunological response to highly active antiretroviral therapy (HAART) at the time of diagnosis and antiparasitic treatment. While the remaining three did not receive prophylaxis, neither did HAART (two of them), but they responded well to treatment. CONCLUSIONS: C. belli is an important cause of diarrhea in HIV patients on HAART and prophylaxis, being able to have different clinical evolution. We suggest that persistent infection may be due to drug failure by intrinsic or extrinsic to the parasite causes, or to defects in restoration of the intestinal immune system, or both. en_US
dc.language.iso spa
dc.publisher SciELO
dc.relation.ispartof urn:issn:0717-6341
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adulto es_PE
dc.subject Humanos es_PE
dc.subject Adulto joven es_PE
dc.subject Persona de Mediana Edad es_PE
dc.subject Estudios Retrospectivos es_PE
dc.subject Infecciones Oportunistas Relacionadas con el SIDA/complicaciones/microbiología es_PE
dc.subject Terapia Antirretroviral Altamente Activa es_PE
dc.subject Coccidiosis/microbiología es_PE
dc.subject Diarrea/etiología/microbiología es_PE
dc.subject Infecciones por VIH/tratamiento farmacológico es_PE
dc.subject Sarcocystidae/microbiología es_PE
dc.subject Combinación Trimetoprim y Sulfametoxazol/uso terapéutico es_PE
dc.subject Perú es_PE
dc.title Infección por Cystoisospora belli en pacientes con VIH: análisis de casos con diferente evolución clínica es_PE
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4067/s0716-10182017000400347
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08


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