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Prevalence of chronic kidney disease in Peruvian primary care setting

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dc.contributor.author Herrera-Añazco, Percy
dc.contributor.author Taype-Rondan, Alvaro
dc.contributor.author Lazo Porras, María de los Ángeles
dc.contributor.author Alberto Quintanilla, E.
dc.contributor.author Ortiz-Soriano, Victor Manuel
dc.contributor.author Hernandez, Adrian V.
dc.date.accessioned 2019-01-25T15:28:08Z
dc.date.available 2019-01-25T15:28:08Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4731
dc.description.abstract BACKGROUND: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. METHODS: We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes (KDIGO). Factors associated with CKD were evaluated with Poisson Regression models; these factors included age, gender, type 2 diabetes mellitus (DM2), hypertension (HTN), body mass index (BMI), and uric acid. Associations were described as crude and adjusted prevalence ratios (PR) and their 95% confidence intervals (95% CI). RESULTS: We evaluated 1211 patients (women [59%], mean age 65.8 years [SD: 12.7]). Prevalence of CKD was 18%. Using the estimated glomerular filtration rate (eGFR), the prevalence was 9.3% (95% CI 5.3 - 13.3) in patients without HTN or DM2; 20.2% (95% CI 17.6 - 22.8) in patients with HTN, and 23.9% (95% CI 19.4 - 28.4) in patients with DM2. The most common stages were 1 and 2 with 41.5% and 48%, respectively. Factors associated with CKD in the adjusted analysis were: age in years (PR = 1.03, 95% CI 1.01 - 1.04), DM2 (PR = 3.37, 95% CI 1.09 - 10.39), HTN plus DM2 (PR = 3.90, 95% CI 1.54 - 9.88), and uric acid from 5 to <7 mg/dL (PR = 2.04, 95% CI 1.31 - 3.19) and ≥7 mg/dL (PR = 5.19, 95% CI 3.32 - 8.11). CONCLUSIONS: Prevalence of CKD in the primary care setting population was high. CKD is more frequent in the early stages of the disease, and individuals with hypertension, DM2, older age and hyperuricemia have higher prevalence of CKD. en_US
dc.language.iso eng
dc.publisher BioMed Central
dc.relation.ispartofseries BMC Nephrology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Aged en_US
dc.subject Aged, 80 and over en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Peru/epidemiology en_US
dc.subject Prevalence en_US
dc.subject Primary Health Care/trends en_US
dc.subject Renal Insufficiency, Chronic/diagnosis/epidemiology/therapy en_US
dc.subject Retrospective Studies en_US
dc.title Prevalence of chronic kidney disease in Peruvian primary care setting en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1186/s12882-017-0655-x
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.20
dc.relation.issn 1471-2369


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