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Subcutaneous mycoses in Peru: a systematic review and meta-analysis for the burden of disease

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dc.contributor.author Ramírez-Soto, M. C.
dc.contributor.author Málaga, Germán
dc.date.accessioned 2019-01-25T16:03:21Z
dc.date.available 2019-01-25T16:03:21Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4767
dc.description.abstract BACKGROUND: There is a worrying lack of epidemiological data on the geographical distribution and burden of subcutaneous mycoses in Peru, hindering the implementation of surveillance and control programs. OBJECTIVES: This study aimed to estimate the disease burden of subcutaneous mycoses in Peru and identify which fungal species were commonly associated with these mycoses. METHODS: We performed a meta-analysis after a systematic review of the published literature in PubMed, LILACS, and SciELO to estimate the burden of subcutaneous mycoses in 25 regions in Peru. The disease burden was determined in terms of prevalence (number of cases per 100,000 inhabitants) and the number of reported cases per year per region. RESULTS: A total of 26 studies were eligible for inclusion. Results showed that sporotrichosis was the most common subcutaneous mycosis (99.7%), whereas lobomycosis, chromoblastomycosis, and subcutaneous phaeohyphomycosis were rare. Cases of eumycetoma and subcutaneous zygomycosis were not found. Of the 25 regions, the burden of sporotrichosis was estimated for four regions classified as endemic; in nine regions, only isolated cases were reported. The highest burden of sporotrichosis was in Apurimac (15 cases/100,000 inhabitants; 57 cases/year), followed by Cajamarca (3/100,000 inhabitants; 30/year), Cusco (0.5/100,000 inhabitants; 4/year), and La Libertad (0.2/100,000 inhabitants; 2/year). In two regions, the mycoses predominantly affected children. CONCLUSIONS: Sporotrichosis is the most common subcutaneous mycosis in Peru, with a high disease burden in Apurimac. Chromoblastomycosis, lobomycosis, and subcutaneous phaeohyphomycosis are rare mycoses in Peru. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartof urn:issn:1365-4632
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Endemic Diseases en_US
dc.subject Subcutaneous Tissue en_US
dc.subject Chromoblastomycosis/epidemiology en_US
dc.subject Humans en_US
dc.subject Lobomycosis/epidemiology en_US
dc.subject Peru/epidemiology en_US
dc.subject Phaeohyphomycosis/epidemiology en_US
dc.subject Sporotrichosis/epidemiology en_US
dc.title Subcutaneous mycoses in Peru: a systematic review and meta-analysis for the burden of disease en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1111/ijd.13665
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE

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