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dc.contributor.author | Castillo-Tokumori, Franco | |
dc.contributor.author | Irey-Salgado, Claudia | |
dc.contributor.author | Málaga Rodríguez, Germán Javier | |
dc.date.accessioned | 2019-01-25T16:20:56Z | |
dc.date.available | 2019-01-25T16:20:56Z | |
dc.date.issued | 2017 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/4800 | |
dc.description.abstract | OBJECTIVES: There has been a sustained and dramatic increase in community-acquired urinary tract infections (CA-UTI) caused by extended-spectrum beta-lactamase (ESBL)-producing bacteria over recent years. Despite this, no studies have been performed in low- or middle-income countries. The main objective of this case-control study was to describe ESBL CA-UTI and its risk factors. METHODS: Outpatients with CA-UTI seen at the Hospital Cayetano Heredia during 2015 were identified. Patients were contacted by telephone. After consent had been obtained, a questionnaire concerning previously identified risk factors was applied. Univariate and multivariate analyses were conducted using Stata version 13. RESULTS: The overall frequency of ESBL-producing Escherichia coli was 40.85%. Sixty-seven cases and 105 controls were included in this study. The following main risk factors were identified on multivariate analysis: previous antibiotic use (odds ratio (OR) 3.09), previous hospitalization (OR 2.92), and previous surgery (OR 2.75). Chronic corticosteroid use (OR 24.32, 95% confidence interval 2.39-246.92) was also identified as a risk factor. CONCLUSIONS: ESBL E. coli accounted for more than 40% of CA-UTIs during 2015. A history of previous hospitalization, surgery, and antibiotic use should be considered when treating this type of infection. Action should be taken to confirm these worrisome results and avoid the major consequences for public health. | en_US |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.relation.ispartofseries | International Journal of Infectious Diseases | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | Anti-Bacterial Agents/therapeutic use | en_US |
dc.subject | beta-Lactamases/biosynthesis | en_US |
dc.subject | Case-Control Studies | en_US |
dc.subject | Community-acquired infection | en_US |
dc.subject | Community-Acquired Infections/drug therapy/epidemiology/microbiology | en_US |
dc.subject | Drug Resistance, Multiple, Bacterial | en_US |
dc.subject | ESBL | en_US |
dc.subject | Escherichia coli | en_US |
dc.subject | Escherichia coli Infections/epidemiology/microbiology | en_US |
dc.subject | Escherichia coli/drug effects/isolation & purification/metabolism | en_US |
dc.subject | Female | en_US |
dc.subject | Hospitalization | en_US |
dc.subject | Humans | en_US |
dc.subject | Male | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Multivariate Analysis | en_US |
dc.subject | Peru/epidemiology | en_US |
dc.subject | Public Health | en_US |
dc.subject | Risk Factors | en_US |
dc.subject | Surveys and Questionnaires | en_US |
dc.subject | Urinary tract infection | en_US |
dc.subject | Urinary Tract Infections/drug therapy/epidemiology/microbiology | en_US |
dc.title | Worrisome high frequency of extended-spectrum beta-lactamase-producing Escherichia coli in community-acquired urinary tract infections: a case-control study | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1016/j.ijid.2016.12.007 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.03.08 | |
dc.relation.issn | 1878-3511 |
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