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Nanopartículas de CuO y su propiedad antimicrobiana en cepas intrahospitalarias

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dc.contributor.author Roman, L. E.
dc.contributor.author Castro, F.
dc.contributor.author Maurtua Torres, Dora Jesus
dc.contributor.author Condori, C.
dc.contributor.author Vivas, D.
dc.contributor.author Bianchi, A. E.
dc.contributor.author Paraguay Delgado, F.
dc.contributor.author Solis, J. L.
dc.contributor.author Gomez, M. M.
dc.date.accessioned 2019-01-25T16:36:30Z
dc.date.available 2019-01-25T16:36:30Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4862
dc.description.abstract Using a prototype reactor, CuO nanoparticles (NPs) were synthetized through the precipitation method, starting from CuSO2 center dot 5H(2)O and Cu(CH3COO)(2)center dot H2O. The obtained NPs were characterized by XDR, FT-IR, SEM, and TEM. The antimicrobial activity of the NPs was determined by the plate diffusion method, placing 20 mg of NPs onto four nosocomial strains obtained from north Lima national hospital Intensive-Care Unit (Staphylococcus epidermidis, Aerococcus viridans, Ochrobactrum anthropic, and Micrococcus lylae). NPs characterization revealed that those synthetized from acetate (CuO-Acet) shown pure CuO phase, while those synthetized from sulphate CuO-Sulf shown two phases where CuO was the predominant one, having more than 84%. The crystal domains for CuO-Acet and CuO-Sulf were 15 and 19 nm, respectively. The inhibition halos for the studied strains were larger for CuO-Sulf NPs than CuO-Acet NPs, only Ochrobactrum anthropi displayed similar inhibition halos for both types of NPs. en_US
dc.description.abstract Empleando un prototipo de reactor, se sintetizaron nanopartículas (NPs) de CuO a través del método de precipitación a partir de CuSO25H2O y de Cu(CH3COO)2H2O. Las NPs obtenidas fueron caracterizadas mediante XRD, FT-IR, TEM y SEM. La actividad antimicrobiana de las NPs se determinó mediante el método de difusión en placa, colocando 20 mg de NPs de CuO sobre cuatro cepas intrahospitalarias o nosocomiales aisladas de la Unidad de Cuidados Intensivos de un hospital nacional de Lima norte (Staphylococcus epidermidis, Aerococcus viridans, Ochrobactrum anthropi y Micrococcus lylae). La caracterización de las NPs de CuO demostró que las sintetizadas a partir de acetato (CuO-Acet) presentaron una fase pura de CuO, mientras que las sintetizadas a partir de sulfato (CuO-Sulf) presentaron dos fases, donde la de CuO representó más del 84%. Los dominios cristalinos del CuO-Acet y CuO-Sulf fueron 15 y 19 nm, respectivamente. Los halos de inhibición de las cepas estudiadas fueron mayores para las NPs de CuO-Sulf que para las NPs de CuO-Acet; solo para la cepa Ochrobactrum anthropi se presentaron halos similares para ambos tipos de NPs. es_PE
dc.language.iso spa
dc.publisher Universidad Nacional de Colombia
dc.relation.ispartofseries Revista Colombiana de Química
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Química es_PE
dc.subject Antibacterianos es_PE
dc.subject Nanopartículas es_PE
dc.subject Productos con Acción Antimicrobiana es_PE
dc.title Nanopartículas de CuO y su propiedad antimicrobiana en cepas intrahospitalarias es_PE
dc.title.alternative CuO nanoparticles and their antimicrobial activity against nosocomial strains en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.15446/rev.colomb.quim.v46n3.62386
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.04.00
dc.relation.issn 2357-3791


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